Congenital naevi treated with erbium:YAG laser (Derma K) resurfacing in neonates: clinical results and review of the literature

The British Journal of Dermatology
J U OstertagG A M Krekels

Abstract

Giant congenital melanocytic naevi (CMN) are often disfiguring, potentially malignant pigmented lesions present at birth. Their management is based on two main considerations: attempt to minimize the risk of malignancy and to obtain an acceptable cosmetic result. In the past various approaches have been used to treat these naevi. To describe clinical and histopathological results after treatment of CMN in neonates with erbium:YAG (Er:YAG) laser resurfacing. Ten children with CMN were treated with Er:YAG laser resurfacing in the first weeks of life. Laser ablation was well tolerated by all children and immediate results were good. At a total follow-up ranging from 3 to 36 months we saw good results, with no or minimal repigmentation, in eight of 10 patients. Patients experienced minimal side-effects such as postoperative pain, bleeding and scar formation. Postoperative histopathology showed disappearance of heavily pigmented cells in the upper part of the dermis. Er:YAG laser resurfacing is an effective method of ablating CMN, with minimal scarring and postoperative complications.

References

Aug 1, 1979·Journal of the American Academy of Dermatology·A W KopfP Hennessey
Apr 1, 1979·British Journal of Plastic Surgery·C J Miller, D W Becker
Oct 1, 1977·British Journal of Plastic Surgery·H Johnson
Oct 1, 1976·The British Journal of Dermatology·R G WaltonA J Cox
Jun 1, 1992·The Journal of Pediatrics·R Ruiz-MaldonadoC Durán
Nov 1, 1986·Archives of Dermatology·B J NickoloffA J Cox
Jul 1, 1987·British Journal of Plastic Surgery·A L Moss
Sep 1, 1984·Journal of the American Academy of Dermatology·J A ZitelliJ B Boyd
Jan 1, 1997·Dermatology : International Journal for Clinical and Investigative Dermatology·R RompelJ Petres
Jan 1, 1997·Dermatology : International Journal for Clinical and Investigative Dermatology·D KoperaM Landthaler
May 13, 1998·British Journal of Plastic Surgery·A R KayN S Mercer
May 29, 1998·The British Journal of Dermatology·D CasanovaG Magalon
Aug 25, 1999·Journal of the American Academy of Dermatology·D RatnerD J Fader
Jan 8, 2000·Plastic and Reconstructive Surgery·J D HopkinsI T Jackson
Feb 15, 2000·Clinical and Experimental Dermatology·C M Lawrence
Aug 22, 2000·The British Journal of Dermatology·K M Acland, R J Barlow
Feb 24, 2001·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·J BohnM Aberg
Jan 5, 2002·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·J L Michel, L Caillet-Chomel
Jun 20, 2002·Archives of Dermatology·Linda E De Raeve, Diane I Roseeuw
Oct 10, 2002·British Journal of Plastic Surgery·K LapièreG Krekels
Jan 22, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Markus ZuttHans Peter Bertsch
Jun 10, 2003·Plastic and Reconstructive Surgery·Nicholas ReynoldsNigel Mercer
Jul 16, 2004·Plastic and Reconstructive Surgery·Andrew J WattKevin C Chung
Nov 17, 2004·British Journal of Plastic Surgery·L H ZaalC M A M van der Horst

❮ Previous
Next ❯

Citations

Jun 15, 2007·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·B Konz
Jul 16, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Khalil A Khatri, Liza Burns
Apr 16, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kristel D PolderSuzanne Bruce
Nov 14, 2015·Lasers in Medical Science·Fleta N BrayKeyvan Nouri
Oct 13, 2006·Clinical and Experimental Dermatology·S F RajparS W Lanigan
Dec 17, 2014·Lasers in Medical Science·Harleen AroraKeyvan Nouri
Oct 28, 2017·The British Journal of Dermatology·C A M EggenA Wolkerstorfer
Mar 12, 2015·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Sang Eun LeeKyung Real Lee
May 15, 2009·The British Journal of Dermatology·K KishiT Nakajima
Mar 16, 2017·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Vito Abrusci, Valentina Benzecry
Sep 18, 2007·Clinics in Dermatology·Karen RiggsTatyana R Humphreys
Sep 18, 2012·Journal of the American Academy of Dermatology·Omar A IbrahimiDaniel B Eisen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.