Congenital nasolacrimal duct obstruction in the second year of life: a multicentre trial of management

Eye
J D YoungS A Ogston

Abstract

We studied spontaneous resolution of congenital nasolacrimal duct obstruction in the second year of life and compared this with the cure rate after probings undertaken between the ages of 11 and 15 months. Of the 111 eyes of 95 patients studied, 26 eyes were included in a randomised prospective comparison of probing with spontaneous resolution. A further 63 eyes followed a similar management plan to the randomised group and are reported as an observational study. Thirty of the 50 eyes followed up without treatment resolved spontaneously before the age of 2 years, of which 24 resolved before 18 months. The overall cure rate for probing was 74% compared with 60% for spontaneous resolution. At 15 months of age the randomised study confirmed that probing at 12-14 months is an effective intervention compared with spontaneous resolution (p = 0.04). At 24 months of age probing was superior in both randomised and non-randomised studies, but with increased numbers in the spontaneous resolution groups the difference was no longer statistically significant. Up to 18 months of age the frequency of spontaneous resolution makes delay in probing a viable management option to be discussed with the parents. It will also lead to an overestimate ...Continue Reading

References

Jan 1, 1991·Eye·C J MacEwen, J D Young
Jan 1, 1989·Ophthalmic Plastic and Reconstructive Surgery·M G Welsh, J A Katowitz
Aug 1, 1986·Ophthalmology·J el-MansouryR D Harley
Sep 1, 1985·Ophthalmology·L R NelsonH Menduke
Jan 1, 1993·Ophthalmic Plastic and Reconstructive Surgery·H al-Hussain, A M Nasr
Jul 1, 1962·The British Journal of Ophthalmology·O O Ffooks
Mar 1, 1947·The Journal of Pediatrics·H W PRICE

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Citations

Mar 16, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Igal LeibovitchPeter J Wormald
Dec 25, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Piero SteindlerFrancesco Parmeggiani
Sep 27, 2000·American Journal of Ophthalmology·S G HonavarG N Rao
Feb 27, 2001·The British Journal of Ophthalmology·C J MacEwenP S White
Aug 21, 2003·The British Journal of Ophthalmology·M B KashkouliZ Tabatabaee
May 21, 2005·BMJ : British Medical Journal·Gunn Elisabeth VistAndrew David Oxman
Jan 24, 2013·Clinical Ophthalmology·Didem SerinBahtinur Buttanri
Jun 6, 2008·Journal of Pediatric Ophthalmology and Strabismus·Rajat Maheshwari
Dec 18, 2013·Middle East African Journal of Ophthalmology·Bahram EshragiMohammadreza Akbari
Nov 19, 2013·Japanese Journal of Ophthalmology·Dilek Yuksel, Pınar Altiaylik Ozer
Jun 15, 2007·Seminars in Ophthalmology·Silvana Artioli SchelliniCarlos Roberto Pereira Padovani
Jul 20, 2010·Journal of Pediatric Ophthalmology and Strabismus·Ossama M HakimEssam Elbaz
Dec 1, 2000·Journal of Vascular and Interventional Radiology : JVIR·Y S ChoK B Sung
Aug 18, 2009·Acta Ophthalmologica·Yasuhiro TakahashiDinesh Selva
Jan 18, 2006·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Po-Liang Chen, Chih-Hsien Hsiao
Apr 1, 2014·The British Journal of Ophthalmology·Ma Khin Pyi SonBrian G Mohney
Jun 19, 2001·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·J A GardinerA V Levin
Aug 4, 2016·Journal of Pediatric Ophthalmology and Strabismus·Maria L NapierEibhlin M McLoone
Sep 10, 2016·Indian Journal of Ophthalmology·V Akila RamkumarBipasha Mukherjee
Dec 16, 2016·Journal of Pediatric Ophthalmology and Strabismus·João BeatoFernando Falcão-Reis
Jul 13, 2017·The Cochrane Database of Systematic Reviews·Carisa Petris, Don Liu
Jul 13, 2013·Current Opinion in Ophthalmology·Bruce M Schnall
Nov 5, 2019·The British Journal of Ophthalmology·Tomomichi NakayamaChie Sotozono
Jun 23, 2004·European Journal of Ophthalmology·G Singh Bhinder, H Singh Bhinder
May 9, 2012·European Journal of Ophthalmology·Seydi OkumusIbrahim Erbagci
Oct 27, 2018·Diseases·Aldo VaggeCarlo Enrico Traverso
May 26, 2017·World Journal of Pediatrics : WJP·Miloš FischerChristian Mozet
Nov 19, 2020·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Sanaz FarrokhiJuliane Mehlan
Feb 28, 2002·American Journal of Ophthalmology·Gregg T Lueder

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