PMID: 737099Dec 1, 1978Paper

Congenitally bicuspid aortic valves. Clinicogenetic study of 41 families

British Heart Journal
R EmanuelO Feizi

Abstract

The families of 41 patients with surgically proved isolated bicuspid aortic valves were examined. There were 275 first degree relatives of whom 220 were living, and 188 (85.5%) of these were examined. Seven first degree relatives were found to have aortic valve disease, and in a further 11 there was 'doubtful' evidence of bicuspid aortic valves. In 6 families there was more than 1 affected member and in an additional 7 families there was 1 or more 'doubtful' first degree relative. The minimum family incidence was therefore 14.6 per cent, or 31.7 per cent if 'doubtful' cases were included. The inheritance is most probably multifactorial, but occasionally the condition may occur as an autosomal dominant. The difficulties of diagnosing bicuspid aortic valves before the development of obstruction of left ventricular outflow were encountered and are discussed. The association of a bicuspid aortic valve with asymmetric septal hypertrophy, hypertrophic cardiomyopathy, and Marfan's syndrome was also noted.

References

Dec 1, 1975·British Heart Journal·O Feizi, R Emanuel
Jan 1, 1976·British Medical Bulletin·C O Carter
Apr 1, 1977·British Heart Journal·J P Bound, W F Logan
May 1, 1967·The Annals of Thoracic Surgery·G G LindesmithJ C Jones
May 1, 1970·British Heart Journal·R Emanuel
Dec 1, 1971·The American Journal of Cardiology·S C MitchellJ Park
May 1, 1974·Circulation·N C NandaJ A DeWeese
Jul 1, 1970·The American Journal of Cardiology·W C Roberts
Sep 1, 1968·British Heart Journal·R EmanuelJ Somerville
Sep 1, 1968·British Heart Journal·J Somerville, L McDonald
Sep 1, 1965·British Heart Journal·J M AndersR Emanuel
Apr 1, 1953·British Heart Journal·M CAMPBELL, R KAUNTZE
Sep 1, 1961·British Medical Bulletin·C O CARTER
Jan 1, 1950·British Heart Journal·G A KILOH

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Citations

Dec 31, 1997·Journal of the American College of Cardiology·K HuntingtonK L Chan
Feb 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C C Lamas, S J Eykyn
Apr 9, 2004·Journal of Clinical Microbiology·Xiang Y HanVictor Fainstein
Jan 1, 1993·British Heart Journal·D J KitchinerR Arnold
May 7, 2014·Pediatric Research·Elizabeth M BonacheaVidu Garg
Jul 31, 2014·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·N GrewalA C Gittenberger-de Groot
Apr 1, 1983·British Heart Journal·R EmanuelK O'Brien
Feb 6, 2008·Expert Review of Cardiovascular Therapy·Tamir FriedmanJohn A Elefteriades
Oct 30, 2012·The Journal of Thoracic and Cardiovascular Surgery·Kathleen C KentHarry C Dietz
Jan 1, 1991·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·A V SalgadoE Salcedo
Jan 3, 2016·The Canadian Journal of Cardiology·Gregor AndelfingerHal Dietz
Feb 25, 2009·Critical Care Nursing Clinics of North America·Georgios A HartasMonesha Gupta-Malhotra
Aug 25, 2007·The Journal of Surgical Research·Jay W EllisonThoralf M Sundt
Aug 7, 2007·American Journal of Medical Genetics. Part a·Melissa L LoscalzoHarry C Dietz
May 23, 2013·American Journal of Medical Genetics. Part a·Daniela AlvesMiguel Leão
Nov 1, 2011·Journal of Anatomy·Valentín Sans-ComaJosep M Arqué
Feb 15, 1994·The American Journal of Cardiology·B N Glick, W C Roberts
Mar 1, 1992·International Journal of Cardiology·V Sans-ComaA C Durán
Apr 10, 2016·The American Journal of Medicine·Luca LongobardoBijoy K Khandheria
Jul 10, 2003·Echocardiography·Cindy BrownDalane W Kitzman
Jun 13, 2009·Journal of the American College of Cardiology·Simon BinerKirsten Tolstrup
Feb 1, 1992·Journal of the American College of Cardiology·R T HahnR B Devereux
Jul 6, 2004·Journal of the American College of Cardiology·Linda CripeD Woodrow Benson
May 21, 2013·International Journal of Cardiology·Juan Robledo-CarmonaEduardo De Teresa-Galván
Oct 18, 2016·Current Opinion in Cardiology·Maria G Andreassi, Alessandro Della Corte
Apr 24, 1996·American Journal of Medical Genetics·M ClementiR Tenconi
Sep 1, 2005·Current Problems in Cardiology·Alan C BravermanMarc R Moon
May 18, 2017·Development·Jan Mašek, Emma R Andersson
Oct 1, 1995·Stroke; a Journal of Cerebral Circulation·W I Schievink, B Mokri
Aug 3, 2014·Circulation. Cardiovascular Genetics·Lisa J MartinD Woodrow Benson
Dec 16, 2017·Circulation. Cardiovascular Genetics·Andreas MartinssonJ Gustav Smith
Feb 1, 1985·American Journal of Medical Genetics·S GoldsteinP Sawyer
Jun 3, 2021·International Journal of Molecular Sciences·Alejandro Junco-VicenteIsabel Rodríguez
May 5, 2010·Neurology·Wouter I SchievinkArlys Velebir
Jul 7, 2021·European Heart Journal. Quality of Care & Clinical Outcomes·Idit TesslerDan Gilon
Apr 6, 2017·Heart, Lung & Circulation·Ratnasari PadangJeffrey B Geske

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