Conjugation of micro/nanocurcumin particles to ZnO nanoparticles changes the surface charge and hydrodynamic size thereby enhancing its antibacterial activity against Escherichia coli and Staphylococcus aureus.

Biotechnology and Applied Biochemistry
Soumitra ShomeHrishikesh Upadhyaya

Abstract

Nanobiotechnology-mediated synthesis of ZnO nanoparticles, micro/nanocurcumin, and curcumin-ZnO nanocomposites and their characterization followed by comparative study of their antibacterial, antioxidant, and iron-chelating efficiency at various dosages are discussed. Micro/nanocurcumin and ZnO nanoparticles were synthesized using curcumin and zinc nitrate as precursor and then conjugated by sonication to synthesize curcumin-ZnO nanocomposites. The synthesized nanoparticles were then characterized by using ultraviolet-visible spectroscopy, X-ray diffraction, Scanning electron microscopy, Fourier-transform infrared spectroscopy, and dynamic light scattering analysis. After that, the antibacterial activity of the synthesized nanoparticles was evaluated by the optical density (OD600 ) method against Escherichia coli and Staphylococcus aureus cells. The DPPH (2,2-diphenyl-1-picrylhydrazyl ), hydroxyl radical scavenging activity, and ferrous ion-chelating efficiency of synthesized nanoparticles were evaluated by spectrophotometry analysis. Nanocurcumin (mean zeta potential = -25 mV; average hydrodynamic diameter = 410 nm) based coating of ZnO nanoparticles (mean zeta potential = -15.9 mV; average hydrodynamic diameter = 274 nm) to s...Continue Reading

References

Mar 21, 2006·Free Radical Biology & Medicine·Yan JiaoSuzy V Torti
Nov 15, 2007·Molecular Pharmaceutics·Preetha AnandBharat B Aggarwal
Dec 18, 2007·FEMS Microbiology Letters·Nicole JonesAdhar C Manna
Jun 13, 2008·Chemico-biological Interactions·Tuba Ak, Ilhami Gülçin
Jan 13, 2009·Scandinavian Journal of Work, Environment & Health·Sie Sie SiewEero Pukkala
Jun 6, 2009·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·J ShaikhM N V Ravi Kumar
Mar 10, 2010·Antimicrobial Agents and Chemotherapy·Steven A RogersChristian Melander
Feb 17, 2011·Journal of Agricultural and Food Chemistry· BhawanaNidhi Jain
Nov 29, 2011·Clinical and Experimental Pharmacology & Physiology·Subash C GuptaBharat B Aggarwal
Mar 6, 2012·Chemical Society Reviews·Irene Canton, Giuseppe Battaglia
Jul 31, 2013·Colloids and Surfaces. B, Biointerfaces·Dhaneswar DasSwapan Kumar Dolui
Oct 26, 2013·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Katia Peñuelas-UrquidesMario Bermúdez de León
Jan 24, 2014·BioMed Research International·Ricardo J B PintoTito Trindade
Feb 5, 2014·Journal of Nanobiotechnology·Li ShangGerd Ulrich Nienhaus
May 31, 2014·BioMed Research International·Soheil Zorofchian MoghadamtousiKeivan Zandi
Mar 18, 2015·Journal of Photochemistry and Photobiology. B, Biology·P C NagajyothiHeung Mook Shin
Jun 14, 2015·Techniques in Vascular and Interventional Radiology·Venkatesh P KrishnasamyShawn N Sarin
Jun 26, 2015·Interdisciplinary Toxicology·Monisha JaishankarKrishnamurthy N Beeregowda
Sep 24, 2015·Journal of Food Science and Technology·Lokesh PathakYadvendra Agrawal
Sep 26, 2015·Journal of Nanobiotechnology·Luccas Missfeldt SanchesAna Maria Carmona-Ribeiro
Nov 17, 2015·International Journal of Pharmaceutics·Maobin XiePing Lan
Nov 21, 2015·Saudi Journal of Biological Sciences·Muthuraman Pandurangan, Doo Hwan Kim
Jan 6, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Aleš PanáčekLibor Kvítek
Oct 18, 2016·The Journal of Pharmacy and Pharmacology·Soumitra ShomeHrishikesh Upadhyaya
Nov 11, 2016·Oxidative Medicine and Cellular Longevity·Alexander V IvanovMaria G Isaguliants
Jul 19, 2017·BioFactors·Mohammad MohajeriAmirhossein Sahebkar
Jul 25, 2017·Acta Veterinaria Scandinavica·Mohamed Ibrahim ShaalanMona Saleh
Feb 7, 2018·Frontiers in Microbiology·Koo NagasawaHirokazu Kimura
Feb 23, 2018·Phytotherapy Research : PTR·Maria MantzorouConstantinos Giaginis
Mar 3, 2018·Nanomaterials·Mercedes G MontalbánDavid L Kaplan

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.