Consensus statement on the loco-regional treatment of appendiceal mucinous neoplasms with peritoneal dissemination (pseudomyxoma peritonei)

Journal of Surgical Oncology
Brendan MoranMarcello Deraco

Abstract

Pseudomyxoma peritonei (PMP) is a rare condition mostly originating from low malignant potential mucinous tumours of the appendix. Although this disease process is minimally invasive and rarely causes haematogenous or lymphatic metastases, expectation of long-term survival are limited with no prospect of cure. Recently, the combined approach of cytoreductive surgery (CRS) and perioperative loco-regional chemotherapy (PLC) has been proposed as the standard of treatment for the disease. The present paper summarizes the available literature data and the main features of the comprehensive loco-regional treatment of PMP. The controversial issues concerning the indications and technical methodology in PMP management were discussed through a web-based voting system by internationally known experts. Results were presented for further evaluation during a dedicated session of "The Fifth International Workshop on Peritoneal Surface Malignancy (Milan, Italy, December 4-6, 2006)". The experts agreed that multiple prospective trials support a benefit of the procedure in terms of improved survival, as compared with historical controls. Concerning the main controversial methodological questions, there was an high grade of consistency among the...Continue Reading

References

Jan 1, 1992·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·M A Kahn, R I Demopoulos
Jan 1, 1991·Gastrointestinal Radiology·D HawesR Wira
Jan 1, 1986·Gastroenterology·G ChejfecV E Gould
Jan 1, 1997·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·B M RonnettR J Kurman
Sep 2, 1999·Annals of Oncology : Official Journal of the European Society for Medical Oncology·P CasaliF Cavalli
Jan 6, 2000·Annals of Surgical Oncology·P H Sugarbaker, D Chang
Oct 24, 2000·The British Journal of Surgery·J Esquivel, P H Sugarbaker
Mar 27, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·H YanP H Sugarbaker
May 30, 2002·American Journal of Surgery·Sonia A ButterworthGreg I McGregor
Jul 5, 2002·Clinical Radiology·T V C SulkinB Moran
Apr 30, 2003·The American Journal of Surgical Pathology·Brigitte M Ronnett, Jeffrey D Seidman
Jul 29, 2003·The American Journal of Surgical Pathology·Joseph MisdrajiRobert H Young
Oct 22, 2003·Surgical Oncology Clinics of North America·Brendan J Moran, Thomas D Cecil
Oct 27, 2004·International Journal of Colorectal Disease·Z GünerP Piso
Jun 1, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C PomelD Elias
Jun 4, 2005·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·F Alexander-SefreB Moran
Nov 24, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R M SmeenkF A N Zoetmulder
May 9, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Brendan J Moran
Nov 23, 2006·Diseases of the Colon and Rectum·Elizabeth M MurphyBrendan J Moran
Jul 17, 2007·The British Journal of Surgery·R M SmeenkF A N Zoetmulder

❮ Previous
Next ❯

Citations

Feb 24, 2012·Investigational New Drugs·Krishna PillaiDavid L Morris
Aug 13, 2013·Current Treatment Options in Oncology·Jason E Faris, David P Ryan
Apr 16, 2011·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Álvaro Arjona-SánchezRosa Ortega-Salas
Jun 27, 2009·The Cancer Journal·Pompiliu PisoHans Juergen Schlitt
Aug 20, 2010·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Brendan J Moran
Jul 31, 2012·Gastroenterology Research and Practice·Toshiyuki Kitai
Jul 30, 2009·Annals of Surgical Oncology·Terence C ChuaDavid L Morris
Mar 5, 2013·Annals of Surgical Oncology·Patrick L WagnerHaroon A Choudry
Nov 20, 2013·Langenbeck's Archives of Surgery·Yakup KuluAlexis Ulrich
Mar 19, 2014·Annales de pathologie·Peggy DartiguesFrédéric Bibeau
Mar 19, 2014·Annales de pathologie·Norman John Carr
Jun 3, 2014·Orphanet Journal of Rare Diseases·Afshin AminiDavid Lawson Morris
Dec 7, 2013·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·P BerkovicK Vandecasteele
Mar 28, 2013·World Journal of Surgery·Alvaro Arjona-SanchezSebastián Rufián-Peña
Jul 4, 2009·Digestive Diseases and Sciences·Tu Nguyen, Aijaz Ahmed
Feb 10, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·B MenasselP Rousset
Feb 5, 2013·Current Problems in Surgery·Curtis J WrayTien C Ko
Mar 2, 2010·Surgical Oncology·Alejandra MartínezDenis Querleu
Jul 22, 2015·Annals of Surgical Oncology·Kathrine BjersandPeter Nygren
May 13, 2014·The American Journal of Pathology·Anthony DohanMarc Pocard
Dec 19, 2015·Annals of Surgical Oncology·Jean-Baptiste DelhormeDiane Goéré
Oct 30, 2013·Journal of Surgical Oncology·Kaitlyn J Kelly, Garrett M Nash
Apr 4, 2015·Clinical Case Reports·Abhishek ChauhanMonz Ahmed
Aug 29, 2014·Journal of Surgical Oncology·Shuja AhmedEdward A Levine
Oct 23, 2015·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·P BarriosE Aranda
May 2, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·N AnsariB J Moran
Apr 17, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·B MoranA Venkatasubramaniam
May 13, 2015·ANZ Journal of Surgery·Sebastian SmolarekJurgen Mulsow
Nov 15, 2014·Annals of Surgical Oncology·Kaitlyn J KellyAndrew M Lowy
Sep 14, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A C LordB J Moran
Jan 7, 2015·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Joseph Misdraji
Jun 1, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Y LiuY Yonemura
Sep 21, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J-B DelhormeD Goéré
May 23, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Terence C ChuaDavid L Morris

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.