Consequences of a false-positive mammography result: drug consumption before and after screening

Acta Oncologica
My von Euler-ChelpinElsebeth Lynge

Abstract

Background Previous research showed women experiencing false-positive mammograms to have greater anxiety about breast cancer than women with normal mammograms. To elucidate psychological effects of false-positive mammograms, we studied impact on drug intake. Methods We calculated the ratio of drug use for women with false-positive versus women with normal mammograms, before and after the event, using population-based registers, 1997-2006. The ratio of the ratios (RRR) assessed the impact. Results Before the test, 40.3% of women from the false-positive group versus 36.2% from the normal group used anxiolytic and antidepressant drugs. There was no difference in use of beta blockers. Hormone therapy was used more frequently by the false-positive, 36.6% versus 28.7%. The proportion of women using anxiolytic and antidepressant drugs increased with 19% from the before to the after period in the false-positive group, and with 16% in the normal group, resulting in an RRR of 1.02 (95% CI 0.92-1.14). RRR was 1.03 for beta blockers, 0.97 for hormone therapy. Conclusion(s) Drugs used to mitigate mood disorders were used more frequently by women with false-positive than by women with normal mammograms already before the screening event, whi...Continue Reading

References

Mar 21, 2006·European Journal of Epidemiology·My von Euler-ChelpinElsebeth Lynge
Jul 14, 2007·Journal of Medical Screening·Sisse Helle NjorElsebeth Lynge
Oct 27, 2007·Acta Obstetricia Et Gynecologica Scandinavica·Ellen LøkkegaardTorben Jørgensen
May 10, 2008·Acta Oncologica·Sune Bangsbøll AndersenMy von Euler-Chelpin
Jan 10, 2009·International Journal of Cancer. Journal International Du Cancer·Sisse Helle NjorElsebeth Lynge
Apr 2, 2010·Statistical Methods in Medical Research·Rebecca A HubbardRobert A Smith
Aug 4, 2011·Scandinavian Journal of Public Health·Helle Wallach KildemoesJesper Hallas
Aug 4, 2012·Evidence-based Medicine·Mary BondChristopher J Hyde
Feb 28, 2013·BMJ : British Medical Journal·Sisse Helle NjorElsebeth Lynge
Mar 20, 2013·Annals of Family Medicine·John Brodersen, Volkert Dirk Siersma
Apr 2, 2013·Health Technology Assessment : HTA·M BondC Hyde
Jun 8, 2013·British Journal of Cancer·M G MarmotM Wilcox
May 7, 2015·International Journal of Cancer. Journal International Du Cancer·Katja Kemp JacobsenMy von Euler-Chelpin
Jun 4, 2015·The New England Journal of Medicine·Béatrice Lauby-SecretanUNKNOWN International Agency for Research on Cancer Handbook Working Group

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