Consequences of being born small for gestational age on body composition: an 8-year follow-up study

The Journal of Clinical Endocrinology and Metabolism
T MeasC Lévy-Marchal

Abstract

Increased fat mass has been reported in children and adults born small for gestational age (SGA). However, the progression of anthropometric parameters have been poorly documented in SGA adults. We hypothesized that SGA individuals would remain susceptible to gain more fat when adults beyond the period of postnatal catch-up growth. From a community-based cohort, 389 subjects born full-term SGA (body weight < 10th percentile) were compared with 462 subjects born appropriate for gestational age (25th < body weight < 75th percentile). Anthropometric parameters were measured at 22 and 30 yr as well as body composition (by multifrequency bioelectrical impedancometry and skinfold thickness) at 30 yr. Both groups gained weight, body mass index (BMI), and waist circumference. Progression of BMI was significantly greater in SGA (1.8 +/- 2.6 vs. 1.4 +/- 2.6 kg/m(2); P = 0.03). At 30 yr, the proportion of obese individuals was significantly increased in SGA (12.1 vs. 6.5%; P = 0.02), and percent body fat was significantly higher (23.5 +/- 8.7 vs. 21.9 +/- 8.0%; P = 0.01), the observation of which was confirmed by skinfold measures. Similarly, waist circumference gain was significantly greater in SGA (6.4 +/- 7.6 vs. 5.5 +/- 7.9, P = 0.04 ...Continue Reading

References

Aug 12, 1976·The New England Journal of Medicine·G P RavelliM W Susser
Sep 1, 1981·The American Journal of Clinical Nutrition·G EnziF Rubaltelli
May 1, 1997·Biological Reviews of the Cambridge Philosophical Society·M Desai, C N Hales
Jun 22, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·Stefano CianfaraniF Branca
Jul 23, 1999·BMJ : British Medical Journal·A LucasT J Cole
Oct 28, 1999·The American Journal of Clinical Nutrition·A C RavelliO P Bleker
Apr 25, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·D JaquetC Lévy-Marchal
Dec 26, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·S P GarnettT J Boulton
Jan 16, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·D KuhM E J Wadsworth
Aug 8, 2002·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·C S Yajnik
Oct 28, 2003·Diabetes Care·Johan G ErikssonDavid J P Barker
Dec 24, 2004·Diabetes Care·Eva Lind RasmussenAllan Vaag
Mar 16, 2006·The Journal of Clinical Endocrinology and Metabolism·Lourdes IbáñezFrancis de Zegher
Oct 13, 2006·The Journal of Clinical Endocrinology and Metabolism·Ulf EkelundStephan Rössner
Jan 17, 2008·Nestlé Nutrition Workshop Series. Paediatric Programme·Johan G Eriksson
Feb 7, 2008·The Journal of Clinical Endocrinology and Metabolism·Abel Lopez-BermejoLourdes Ibáñez

Citations

Mar 23, 2010·Maternal and Child Health Journal·Sohyun ParkDiana M Bensyl
Apr 1, 2011·Journal of Developmental Origins of Health and Disease·N MatobaX Wang
Feb 25, 2010·Current Opinion in Clinical Nutrition and Metabolic Care·Nicolas Stettler, Violeta Iotova
Mar 9, 2010·Nutrition & Metabolism·Etienne PouteauKatherine Macé
Aug 8, 2014·Journal of Human Genetics·Clara Y CheongWalter Stünkel
Dec 2, 2014·Obesity Research & Clinical Practice·Ramona StroescuGabriela Doroş
Jan 21, 2012·Early Human Development·Maria Lorella GiannìFabio Mosca
Mar 5, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·M N KooijmanVwv Jaddoe
Dec 19, 2015·American Journal of Human Biology : the Official Journal of the Human Biology Council·Megan WorkmanJoe Alcock
Dec 17, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·T D BrisboisL J McCargar
Oct 12, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·G V Araújo de FrançaC G Victora
Jan 20, 2015·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M Z KapadiaS D McDonald
May 21, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·E MurrayA Stein
Sep 27, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Giuseppe SaggeseFrancesca Simi
Apr 26, 2013·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Frank M Biro, Julianna Deardorff
Aug 18, 2016·Scientific Reports·Justin D CraneKatherine M Morrison
Apr 1, 2017·Archives of Disease in Childhood·Fenny BeukersAleid G van Wassenaer-Leemhuis
Mar 8, 2018·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Adrian J GreenAntonio Planchart
Jun 21, 2011·Annals of Human Biology·Caroline H D Fall
Apr 10, 2014·The Journal of Clinical Endocrinology and Metabolism·Olta GishtiVincent W V Jaddoe
Oct 20, 2009·The Journal of Clinical Endocrinology and Metabolism·Gerthe F KerkhofAnita C S Hokken-Koelega
Jul 22, 2019·Current Diabetes Reports·Elvira Isganaitis
Oct 17, 2020·Childhood Obesity·Susi Araújo AlvesJoão Guilherme Alves

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