Consequences of Domestication on Gut Microbiome: A Comparative Study Between Wild Gaur and Domestic Mithun

Frontiers in Microbiology
Vandana R PrabhuMuniyandi Nagarajan

Abstract

Although the gut microbiome benefits the host in several ways, how anthropogenic forces impact the gut microbiome of mammals is not yet completely known. Recent studies have noted reduced gut microbiome diversity in captive mammals due to changes in diet and living environment. However, no studies have been carried out to understand how the gut microbiome of wild mammals responds to domestication. We analyzed the gut microbiome of wild and captive gaur and domestic mithun (domestic form of gaur) to understand whether the gut microbiome exhibits sequential changes from wild to captivity and after domestication. Both captive and domestic populations were characterized by reduced microbial diversity and abundance as compared to their wild counterparts. Notably, two beneficial bacterial families, Ruminococcaceae and Lachnospiraceae, which are known to play vital roles in herbivores' digestion, exhibited lower abundance in captive and domestic populations. Consequently, the predicted bacterial functional pathways especially related to metabolism and immune system showed lower abundance in captive and domestic populations compared to wild population. Therefore, we suggest that domestication can impact the gut microbiome more severely...Continue Reading

References

Apr 30, 1998·Critical Reviews in Microbiology·R Nandi, S Sengupta
Apr 14, 2004·Journal of Applied Microbiology·M M WilliamsH S Rochon
Mar 26, 2005·Science·Fredrik BäckhedJeffrey I Gordon
Jul 11, 2007·Proceedings of the National Academy of Sciences of the United States of America·Yann MarcyStephen R Quake
Jan 9, 2008·Nature Reviews. Microbiology·Harry J FlintBryan A White
May 24, 2008·Science·Ruth E LeyJeffrey I Gordon
Nov 20, 2008·Journal of Medical Microbiology·Tanja KuehbacherStephan J Ott
Apr 13, 2010·Nature Methods·J Gregory CaporasoRob Knight
Aug 17, 2010·Bioinformatics·Robert C Edgar
Sep 10, 2010·The ISME Journal·Catherine LozuponeRob Knight
Sep 25, 2010·Nature Reviews. Immunology·Nadine Cerf-Bensussan, Valérie Gaboriau-Routhiau
Feb 1, 2011·Bioinformatics·Robert Schmieder, Robert Edwards
Jun 16, 2011·FEMS Microbiology Ecology·Alexandre B de MenezesEvelyn M Doyle
Sep 10, 2011·Bioinformatics·Tanja Magoč, Steven L Salzberg
Feb 1, 2012·Genetics and Molecular Research : GMR·K-X QuL-S Zan
Sep 4, 2012·Current Opinion in Biotechnology·Jean Guy LeBlancMarco Ventura
Aug 27, 2013·Nature Biotechnology·Morgan G I LangilleCurtis Huttenhower
Sep 21, 2013·Annual Review of Marine Science·Sergio A Sañudo-WilhelmyEric A Webb
Apr 17, 2014·Nature Communications·Stephanie L SchnorrAlyssa N Crittenden
Jun 3, 2014·BMC Veterinary Research·J Scott WeeseMurray D Jelinski
Dec 30, 2014·Nutrients·Michael A Conlon, Anthony R Bird
Mar 26, 2015·Nature Communications·Alexandra J Obregon-TitoCecil M Lewis
May 20, 2015·Current Biology : CB·Simone RampelliMarco Candela
Dec 23, 2015·Microbiome·Yuanyuan ChengKatherine Belov
Jul 10, 2016·Journal of Molecular Biology·Darrell W Cockburn, Nicole M Koropatkin
Aug 31, 2016·Proceedings of the National Academy of Sciences of the United States of America·Jonathan B ClaytonDan Knights
Jan 14, 2017·Critical Reviews in Food Science and Nutrition·Maria Gabriela Valle GottliebCarla Helena Augustin Schwanke
May 11, 2017·Frontiers in Microbiology·Sarah M Hird
Jul 25, 2017·Microbial Ecology·Vanessa L HaleKatherine R Amato
Sep 25, 2017·Frontiers in Cellular and Infection Microbiology·Cheryl S Rosenfeld
Oct 7, 2017·Integrative and Comparative Biology·Valerie J McKenzieRob Knight

❮ Previous
Next ❯

Datasets Mentioned

BETA
PRJNA595722

Methods Mentioned

BETA
PCR

Software Mentioned

USEARCH
edgeR
vegan package
PRINSEQ
QIIME
FLASH
PICRUSt
lme
CUTADAPT
edgeR package

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.