Consequences of misdiagnosis of lymphomatoid papulosis

European Journal of Cancer Care
S LaubeJ Marsden

Abstract

We report two patients with lymphomatoid papulosis (LyP), who were initially diagnosed as systemic T-cell lymphoma. The patients presented with recurrent self-healing cutaneous lesions and skin biopsies showed a lymphocytic infiltrate with malignant features. Clinico-pathological correlation of findings was not performed and results of staging investigations were misinterpreted. Consequently, both patients were unnecessarily treated with multi-agent chemotherapy, radiotherapy and stem cell/bone marrow transplants and sustained long-term adverse effects. The clinical and histological features of LyP are described and appropriate management discussed in detail. Factors leading to the unnecessary treatment of both patients are examined and several learning points highlighted such as the importance of a multidisciplinary approach.

References

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Citations

Apr 19, 2008·Annales de dermatologie et de vénéréologie·C AllabertA Dompmartin
Feb 28, 2013·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Marco ArdigòMarina Agozzino
Oct 28, 2015·BioMed Research International·Michelle S GentileBharat B Mittal
Jul 13, 2017·American Journal of Hematology·Jacqueline McKeseyHeather Wickless

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