Conservation laryngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer

Head & Neck
F Christopher HolsingerEduardo M Diaz

Abstract

Total laryngectomy is the standard of care for surgical salvage of radiation failure in laryngeal cancer. However, the role of conservation laryngeal surgery in this setting remains unclear. The objective was to compare the efficacy of conservation versus total laryngectomy for salvage of radiation failure in patients who initially presented with T1 or T2 squamous cancer of the larynx. A 21-year retrospective analysis of patients who received surgery at a single comprehensive cancer center after definitive radiation therapy is reported. At recurrence, the patients were reevaluated and then underwent a total laryngectomy or, if possible, a conservation laryngeal procedure. The charts of 105 patients who failed radiation treatment for primary laryngeal cancer and who subsequently underwent surgical salvage were reviewed for this study. Eighty-nine were male (84.8%). The mean age was 60.3 years. The median follow-up time after surgery was 69.4 months. Most patients with recurrence after radiotherapy required total laryngectomy (69.5%; 73/105). Conservation laryngeal surgery was performed for 32 patients (31.5%). Concomitant neck dissections were performed on 45 patients (45.5%). In 14 patients, local or regional recurrence develop...Continue Reading

References

Dec 1, 1977·The Laryngoscope·H M Tucker
May 1, 1976·The Laryngoscope·L W DeSantoK D Devine
Feb 1, 1991·Cancer·L VianiJ E Dalby
Oct 1, 1991·American Journal of Surgery·R S Lavey, T C Calcaterra
Jan 1, 1974·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·A J Ballantyne, G H Fletcher
Apr 1, 1968·Cancer·C A PerezW E Powers
Nov 1, 1966·Archives of Otolaryngology·C M Norris, A R Peale
Nov 1, 1994·American Journal of Surgery·G SchwaabB Luboinski
Apr 1, 1996·The Laryngoscope·O LaccourreyeD Brasnu
Dec 1, 1996·American Journal of Surgery·W M LydiattK M Lydiatt
Sep 1, 1951·The Annals of Otology, Rhinology, and Laryngology·M L SOM

❮ Previous
Next ❯

Citations

Oct 18, 2013·The Journal of Laryngology and Otology·U AydilA Köybaşioğlu
Mar 11, 2008·Current Opinion in Otolaryngology & Head and Neck Surgery·Gino MarioniAlberto Staffieri
Mar 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F Christopher HolsingerFadlo R Khuri
Mar 14, 2014·Current Oncology Reports·Mark Zafereo
Mar 29, 2014·American Journal of Otolaryngology·Marianne AbouyaredZoukaa Sargi
May 16, 2008·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Concepción Ferreiro-ArgüellesJuan M Fernández-Gallardo
Apr 8, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·G PsychogiosH Iro
Jul 15, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Carl E SilverAlfio Ferlito
Mar 2, 2011·Oral Oncology·L van der PuttenC R Leemans
Jun 24, 2008·Otolaryngologic Clinics of North America·Ralph P Tufano, Edward M Stafford
Oct 18, 2007·International Journal of Radiation Oncology, Biology, Physics·Russell B Smith
Nov 23, 2006·Oral Oncology·Eric M GendenAlessandra Rinaldo
Aug 5, 2008·The Laryngoscope·VyVy N YoungJeffrey M Bumpous
Apr 13, 2011·Head & Neck·Ivan Marcelo Gonçalves AgraLuiz P Kowalski
Mar 9, 2013·Head & Neck·Allen S HoLuc G T Morris
Sep 2, 2014·Journal of Surgical Oncology·Marat MuhamedovValentina Hodorenko
Apr 3, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Valesca P RetèlMichiel W van den Brekel
Aug 4, 2015·Otolaryngologic Clinics of North America·Michelle Mizhi ChenOllivier Laccourreye
Mar 29, 2013·The Annals of Otology, Rhinology, and Laryngology·Jong Chul HongKang Dae Lee
Jun 29, 2012·The Annals of Otology, Rhinology, and Laryngology·Young Jin HanKang Dae Lee
Nov 21, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Hassan ArshadWesley L Hicks
Sep 10, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Clint T AllenAlbert L Merati
Jan 4, 2017·Clinical and Experimental Otorhinolaryngology·UNKNOWN Korean Society of Thyroid-Head and Neck Surgery Guideline Task ForceKang Dae Lee
May 13, 2017·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·J W ParkS Y Song
May 24, 2013·The Annals of Otology, Rhinology, and Laryngology·Anca M BarbuSteven M Zeitels
Jul 14, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jonathan J LusardiMark A Varvares
Jan 3, 2018·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Shayan CheraghlouBenjamin L Judson
Nov 28, 2017·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Arlene A ForastiereGregory T Wolf
Jan 24, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Joris B W ElbersCharlotte L Zuur
Feb 1, 2019·Acta Oto-laryngologica·Ji Hoon KimEun Chang Choi
Mar 31, 2016·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Rachel S MandelbaumAbie H Mendelsohn
Feb 12, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Philippe GorpheFrançois Janot

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.