Conservative excisional laser conization for early invasive cervical cancer

Gynecologic Oncology
Masatsugu UedaM Ueki

Abstract

To investigate the possibility of conservative excisional laser conization for early invasive cervical cancer. Four hundred one women with early invasive squamous cell cancer were treated by laser conization and semiradical or radical hysterectomy with pelvic lymphadenectomy. Their histologic findings and clinical outcomes were evaluated retrospectively. Two hundred Ia1 cases without confluent invasion or vessel permeation receiving only laser therapy had no recurrent disease. There was no lymph node metastasis in 123 Ia1 and 24 Ia2 cases with stromal invasion of under 4 mm in depth regardless of confluent invasion and vessel permeation. However, lymph node metastasis was detected in 1 of 13 Ia2 cases with stromal invasion of over 4 mm in depth and in 5 of 41 Ib1 cases. All of these six cases had vessel permeation in the resected specimens. Conservative excisional laser conization may be possible for stage Ia cervical cancer with stromal invasion of under 4 mm in depth. However, the risk of lymph node metastasis should be still considered for those lesions with vessel permeation.

References

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Citations

Nov 8, 2005·Gynecologic Oncology·Masatsugu UedaMinoru Ueki
Jul 19, 2013·Gynecologic Oncology·Clare J ReadeAllan Covens
Nov 15, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Moza Al-KalbaniW Glenn McCluggage
Mar 5, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Hannah van MeursJacobus van der Velden
Mar 5, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Silvano CostaGiuseppe Pelusi
Aug 5, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Tetsuro YahataKenichi Tanaka
Sep 24, 2005·The Oncologist·Mario M Leitao, Dennis S Chi

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