Conservative management of cervical cancer: Current status and obstetrical implications

Best Practice & Research. Clinical Obstetrics & Gynaecology
Joël Fokom Domgue, Kathleen M Schmeler

Abstract

Recent advances in screening and early diagnosis have decreased cervical cancer incidence and mortality rates in high-resource settings. The postponement of childbearing, combined with an increased number of cervical cancer survivors, has yielded new paradigms in patient care. In recent years, radical surgery has been challenged as the standard of care for early-stage cervical cancer owing to its significant morbidity and fertility impairment. Attention has been directed to assessing more conservative procedures that can reduce treatment-induced morbidity without compromising oncologic safety and reproductive potential of patients with early-stage disease. In those with more advanced disease, neoadjuvant chemotherapy followed by conservative surgery has also been considered. These conservative treatment modalities including cervical conization, simple trachelectomy, and simple hysterectomy have been studied in various settings. In this chapter, we discuss the role of conservative surgery in the management of cervical cancer and the resulting obstetrical outcomes.

Citations

Jun 6, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Marie PlanteJean Gregoire
Aug 3, 2020·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Thibaut RaginelLydia Guittet
Oct 2, 2020·International Journal of Environmental Research and Public Health·Chia-Yi LeeWen-Fang Cheng
Dec 5, 2020·Critical Reviews in Oncology/hematology·Xiangxuan ZhaoZaiming Lu
Dec 9, 2020·Critical Reviews in Oncology/hematology·Zahra Sadat RazaviHamed Mirzaei
Mar 3, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Javier BurbanoJuliana Rodriguez
Mar 3, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Fabio MartinelliFrancesco Raspagliesi
Sep 9, 2020·Critical Reviews in Oncology/hematology·Edgardo SomiglianaFedro Peccatori
Aug 26, 2021·Journal of Gynecologic Oncology·Violante Di DonatoLudovico Muzii

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