Conservative management of preterm premature rupture of membranes beyond 32 weeks' gestation: is it worthwhile?

Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology
Z TsafrirA Many

Abstract

We aimed to investigate whether conservative management of preterm premature rupture of membranes (PPROM) at 32-34 weeks' gestation improves outcome. In this retrospective analysis of singleton pregnancies, the study group included patients with PPROM at 28-34 weeks' gestation and the control group included patients presented with spontaneous preterm delivery at 28-34 weeks' gestation. Both groups were subdivided according to gestational age - early (28-31 weeks' gestation) versus late (32-34 weeks' gestation). Adverse neonatal outcome included neonatal death, intraventricular haemorrhage grade 3/4, respiratory distress syndrome, periventricular leucomalacia and neonatal sepsis. The study and control groups included 94 and 86 women, respectively. The study group had a lower incidence of adverse neonatal outcome at the earlier weeks (28-31), compared with the control group at the same gestational age. In contrast, at 32-34 weeks' gestation no difference in the risk for adverse neonatal outcome was noticed. Additionally, within the study group, chorioamnionitis rate was significantly higher among those who delivered at 32-34 weeks' gestation (p < 0.01). No advantage for conservative management of PPROM was demonstrated beyond 31 ...Continue Reading

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Citations

Jun 18, 2019·BJOG : an International Journal of Obstetrics and Gynaecology·A J Thomson, UNKNOWN Royal College of Obstetricians and Gynaecologists
Mar 14, 2019·Scientific Reports·Hanane BouchghoulMarie-Victoire Senat

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