Conservative Treatment of Chronic Subdural Hematoma in HIV-Associated Thrombocytopenia with Tranexamic Acid

Journal of the International Association of Providers of AIDS Care
Raja K KuttyM Anilkumar

Abstract

Chronic subdural hematomas (CSDHs) and its management comprise a majority work in a neurosurgical specialty. The effectiveness of surgery is beyond doubt and sometimes even lifesaving in severe cases. However, the straightforward surgery is sometimes complicated by the associated comorbidities of the patient. Comorbidities in the form of coagulopathies secondary to chronic liver diseases, drugs (warfarin, ecosprin, clopidogrel), thrombocytopenia secondary to systemic illness are always a challenge to deal with in patients with CSDH. The authors encountered a patient with thrombocytopenia secondary to systemic HIV infection who presented with CSDH. Her coagulation profile was severe enough to preclude surgery. She was managed conservatively with tranexamic acid and responded well. The authors present the challenges they faced in the course of successful management of this patient.

Associated Clinical Trials

References

Aug 1, 1983·Journal of Neurosurgery·T YamashimaR L Friede
Dec 23, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·B Vujkovac, M Sabovic
Jan 18, 2006·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Aleksa CenicKesava Reddy
Jun 14, 2012·Advances in Hematology·Kimberley L S AmblerHeather A Leitch
May 7, 2013·Journal of Neurosurgery·Hiroshi KageyamaKazunari Oka
Nov 26, 2013·Journal of the Neurological Sciences·Dong WangJianning Zhang

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Citations

Jan 21, 2020·Expert Opinion on Pharmacotherapy·Jinhao HuangRongcai Jiang
Aug 3, 2021·British Journal of Neurosurgery·Roger LodewijkxDagmar Verbaan

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Methods Mentioned

BETA
enzyme-linked immunosorbent assays

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