Conservative versus surgical treatment of venous leg ulcers: 10-year follow up of a randomized, multicenter trial

Phlebology
W B van GentC H Wittens

Abstract

Leg ulcers have a large socio-economic impact. Treatment modalities are either conservative or surgical. Conservative treatment involves local treatment and compression therapy. Surgical treatment of venous ulcers is based on correcting venous hypertension, by treating incompetent superficial, deep, and perforating veins. A prospective randomized multicenter trial comparing surgical treatment (combined superficial and perforating vein surgery) with ambulatory compression therapy was conducted during 1998 and 2001. This paper presents the results of a 10-year follow-up period of this trial. All patients enrolled in the original prospective trial were approached and invited for additional examination and duplex ultrasound evaluation. Secondary, disease specific and generic quality-of-life (QoL) was assessed. Current ulcer state and recurrence during the follow-up period was assessed. After a mean of 97 months follow up, 80 (41%) out of 196 legs could be inspected. The incidence of "ulcer-free", the main outcome, was significantly (p = 0.007) higher in the surgical group (58.9%), compared to the conservative group (39.6%). Observed ulcer recurrence was 48.9% for the surgical group and 94.3% for the conservative group. The number o...Continue Reading

References

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Citations

Jul 29, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Ashley WysongLeland Housman
Jul 7, 2017·The International Journal of Lower Extremity Wounds·Julian VitseLuc Teot
Jun 20, 2018·The Indian Journal of Surgery·Ravul JindalRoy Varghese
Aug 15, 2018·Evidence-based Complementary and Alternative Medicine : ECAM·Minfeng WuFulun Li
Jul 7, 2017·The International Journal of Lower Extremity Wounds·Xiaofang SunTing Xie

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