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Conserved function of ether lipids and sphingolipids in the early secretory pathway

bioRxiv

Dec 19, 2019

Noemi Jiménez-RojoHoward Riezman

Abstract

Sphingolipids have been shown to play important roles in physiology and cell biology, but a systematic examination of their functions is lacking. We performed a genome-wide CRISPRi screen in sphingolipid-depleted cells and identified hypersensitive mutants in genes of membrane trafficki...read more

Mentioned in this Paper

Secretory Pathway
Simulation
Genome
Physiological Aspects
Biological Evolution
Lipogenesis
Regulation of Biological Process
Phosphatidylcholines
Sphingomyelins
Sphingolipids
50
Paper Details
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Conserved function of ether lipids and sphingolipids in the early secretory pathway

bioRxiv

Dec 19, 2019

Noemi Jiménez-RojoHoward Riezman

PMID: 990881094

DOI: 10.1101/2019.12.19.881094

Abstract

Sphingolipids have been shown to play important roles in physiology and cell biology, but a systematic examination of their functions is lacking. We performed a genome-wide CRISPRi screen in sphingolipid-depleted cells and identified hypersensitive mutants in genes of membrane trafficki...read more

Mentioned in this Paper

Secretory Pathway
Simulation
Genome
Physiological Aspects
Biological Evolution
Lipogenesis
Regulation of Biological Process
Phosphatidylcholines
Sphingomyelins
Sphingolipids
50

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p24 family proteins: key players in the regulation of trafficking along the secretory pathway

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Noelia Pastor-CantizanoFernando Aniento
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Paper Details
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