Conserved MYC transcription factors play a key role in jasmonate signaling both in tomato and Arabidopsis

Genes & Development
Marta BoterSalomé Prat

Abstract

Jasmonates (JA) are important regulators of plant defense responses that activate expression of many wound-induced genes including the tomato proteinase inhibitor II (pin2) and leucine aminopeptidase (LAP) genes. Elements required for JA induction of the LAP gene are all present in the -317 to -78 proximal promoter region. Using yeast one-hybrid screening, we have identified the bHLH-leu zipper JAMYC2 and JAMYC10 proteins, specifically recognizing a T/G-box AACGTG motif in this promoter fragment. Mutation of the G-box element decreases JA-responsive LAP promoter expression. Expression of JAMYC2 and JAMYC10 is induced by JA, with a kinetics that precedes that of the LAP or pin2 transcripts. JAMYC overexpression enhanced JA-induced expression of these defense genes in potato, but did not result in constitutive transcript accumulation. Using footprinting assays, an additional protected element was identified, located directly adjacent to the T/G-box motif. Mutation of this element abolishes JA response, showing that recognition of this duplicated element is also required for gene expression. Knockout mutants in the AtMYC2 homolog gene of Arabidopsis are insensitive to JA and exhibit a decreased activation of the JA-responsive gene...Continue Reading

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Citations

Sep 7, 2007·Molecular Genetics and Genomics : MGG·Katsutomo SasakiYuko Ohashi
Sep 18, 2009·Molecular Genetics and Genomics : MGG·Yuanqing JiangMichael K Deyholos
Mar 5, 2013·Functional & Integrative Genomics·Mei-Liang ZhouYan-Min Wu
Mar 12, 2013·Functional & Integrative Genomics·Mei-Liang ZhouYan-Min Wu
Sep 11, 2007·Plant Molecular Biology·Hongmei LiChuanyou Li
Feb 5, 2008·Science in China. Series C, Life Sciences·Ang LiRong-Feng Huang
May 7, 2008·Proceedings of the National Academy of Sciences of the United States of America·Leron KatsirGregg A Howe
Sep 21, 2011·Proceedings of the National Academy of Sciences of the United States of America·Akihiro SuzukiAnn M Hirsch
Dec 21, 2011·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Kyonoshin MaruyamaKazuko Yamaguchi-Shinozaki
Aug 20, 2008·Journal of Experimental Botany·Xiao-Xia ShangguanXiao-Ya Chen
Apr 4, 2009·Journal of Experimental Botany·Haruko OkamotoMarc R Knight
Sep 13, 2008·Molecular Plant-microbe Interactions : MPMI·Mark Kinkema, Peter M Gresshoff
Mar 21, 2008·Plant Physiology·Shinyoung LeeGynheung An
Apr 9, 2008·Plant Physiology·Kemal Kazan, John M Manners

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