Considerable variability in antibiotic use among US children's hospitals in 2017-2018.

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Hannah G GriffithCarlos G Grijalva

Abstract

To characterize the prevalence of and seasonal and regional variation in inpatient antibiotic use among hospitalized US children in 2017-2018. We conducted a cross-sectional examination of hospitalized children. The assessments were conducted on a single day in spring (May 3, 2017), summer (August 2, 2017), fall (October 25, 2017), and winter (January 31, 2018). The main outcome of interest was receipt of an antibiotic on the study day. The study included 51 freestanding US children's hospitals that participate in the Pediatric Health Information System (PHIS). This study included all patients <18 years old who were admitted to a participating PHIS hospital, excluding patients who were admitted solely for research purposes. Of 52,769 total hospitalized children, 19,174 (36.3%) received antibiotics on the study day and 6,575 of these (12.5%) received broad-spectrum antibiotics. The overall prevalence of antibiotic use varied across hospitals from 22.3% to 51.9%. Antibiotic use prevalence was 29.2% among medical patients and 47.7% among surgical patients. Although there was no significant seasonal variation in antibiotic use prevalence, regional prevalence varied, ranging from 32.7% in the Midwest to 40.2% in the West (P < .001)....Continue Reading

References

Mar 1, 1994·The Journal of Antimicrobial Chemotherapy·J F WestphalJ M Brogard
Dec 19, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Timothy H DellitUNKNOWN Society for Healthcare Epidemiology of America
Aug 29, 2009·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Bernard C CaminsHenry M Blumberg
Nov 17, 2010·Pediatrics·Jeffrey S GerberTheoklis E Zaoutis
Jun 16, 2012·Internal Medicine Journal·P R IngramR Murray
Aug 7, 2012·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Phillip D LevinShmuel Benenson
Nov 15, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jeffrey S GerberTheoklis E Zaoutis
Oct 8, 2014·JAMA : the Journal of the American Medical Association·Shelley S MagillUNKNOWN Emerging Infections Program Healthcare-Associated Infections and Antimicrobial Use Prevalence Survey Team
Dec 10, 2014·Pediatrics·Adam L HershJason G Newland
May 4, 2016·JAMA : the Journal of the American Medical Association·Katherine E Fleming-DutraLauri A Hicks
Nov 24, 2016·Blood·Kamilla S JosefsdottirKatherine Y King
Mar 14, 2018·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Thomas V BroganJason G Newland
Apr 25, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kalvin C YuJason Jones
Apr 26, 2018·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Troy RichardsonMatt Hall
May 26, 2018·JAMA : the Journal of the American Medical Association·Craig M HalesCynthia L Ogden

❮ Previous
Next ❯

Citations

Jan 17, 2021·Journal of the Pediatric Infectious Diseases Society·Rebecca G SamePranita D Tamma
Feb 3, 2021·Journal of the Pediatric Infectious Diseases Society·Rina A FergusonJason G Newland
Dec 16, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rachel L WattierUNKNOWN Pediatric Health Information System Antimicrobial Stewardship Research Group
Sep 10, 2021·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Hillary J J SpencerLeigh M Howard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.