Consideration of vaccination against the FSGS factor

Medical Hypotheses
E L Altschuler

Abstract

Focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic disease in adults, and it is thought to be increasing in incidence. FSGS is often difficult to treat and even has a high propensity to relapse after transplant. Indeed, this suggests that there might be some circulating factor responsible for proteinuria ('FSGS factor'). Here I suggest that if and when the FSGS factor is found, vaccination against this factor might be a useful treatment modality for FSGS.

References

Mar 12, 1999·Journal of the American Society of Nephrology : JASN·M SharmaV J Savin
Jun 26, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·S M Korbet
Feb 24, 2001·The New England Journal of Medicine·M J KemperD E Müller-Wiefel

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