Considerations for epidural anesthesia in a patient with type 1 von Willebrand disease.

Journal of Anesthesia
Koji HaraTakeyoshi Sata

Abstract

Epidural anesthesia, combined with general anesthesia, was performed in a patient with type 1 von Willebrand disease (VWD). VWD is a common inherited bleeding disorder, and an anesthetic concern in patients with VWD is susceptibility to postoperative bleeding and epidural or spinal hematoma associated with neuraxial block. After confirming the patient's responsiveness to 1-desamino-8-D-arginine vasopressin (DDAVP) and obtaining informed consent, epidural anesthesia was performed to avoid the use of analgesics that inhibit platelet function. The patient's postoperative course was uneventful. Epidural anesthesia could be one of the choices of treatment for postoperative pain in those patients with type 1 VWD for whom the conditions discussed are fulfilled, to ensure safe usage of this technique.

Citations

Aug 27, 2014·Seminars in Perinatology·Antonio Gonzalez-Fiol, Andrew Eisenberger
May 13, 2021·Research and Practice in Thrombosis and Haemostasis·Wynn PetersonMichelle Sholzberg

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