journal cover

Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats

BMC Genomics

Oct 30, 2010

Shoshana GreenbergerEli Eisenberg

Abstract

Adenosine to inosine (A-to-I) RNA-editing is an essential post-transcriptional mechanism that occurs in numerous sites in the human transcriptome, mainly within Alu repeats. It has been shown to have consistent levels of editing across individuals in a few targets in the human brain and...read more

Mentioned in this Paper

Neuro-Oncological Ventral Antigen 2
Guanosine
Conserved Sequence
Untranslated Regions
Exons
Adenosine
Lung
Enzymes, antithrombotic
THOC5 gene
RNA, Double-Stranded
Paper Details
References
  • References38
  • Citations20

Similar Papers Found In These Feeds

Structure and Function of DNA

The double helix structure of DNA is important for its biological function. Discover the latest research on the Structure and Function of DNA here.

Epigenome Engineering (Keystone)

Recent advances in epigenome engineering technologies allow now for the large-scale assessment of the functional relevance of DNA methylation. Discover the latest research here.

Perturb-seq

Perturb-seq has combined CRISPR gene inactivation and single-cell rna-sequencing (scRNA-seq) and is the newest addition to the geneticist's arsenal, providing scientists with study methods for functional genomics. Discover the latest research here.

Epigenome Engineering

Recent advances in epigenome engineering technologies allow now for the large-scale assessment of the functional relevance of dna methylation. Discover the latest research here.

Exon Skipping

Exon skipping is a method of RNA splicing used when a mutation occurs in the genes of exons. It is regulated largely by the use of antisense oligonucleotides that mask the mutated gene and allow the cellular machinery to skip over it. Exon skipping is being investigated as a therapeutic option for some diseases. Here is the latest research on exon skipping.

Nucleolar Dynamics

The nucleolus is the site of ribosome biogenesis, making ribosomal subunits from proteins and ribosomal RNA. Discover the latest research on nucleolar dynamics here.

Human Lung Cell Atlas

Examining the genomics, transcriptomics, proteomics, and metabolomics of the human lung at the single cell level will help build a single cell atlas of the lungs, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the lungs. Discover the latest research on the human cell lung atlas here.

RNA Splicing

The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA Splicing here.

Inosine: Parkinson's Disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects movement. Drug Inosine is proposed to slow progression of this disease. Here is the latest research on Inosine in PD.

RNA Splicing (Keystone)

The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA splicing and co-transcriptional splicing in this feed.

MicroRNAs & Open Reading Frames

MicroRNAs are small non-coding RNAs that modulate gene expression at post-transcriptional level, playing a crucial role in cell differentiation and development. Discover the latest research on MicroRNAs & how they target Open Reading Frames.

RNA Editing and ADAR Enzymes

ADAR enzymes are responsible for a-to-i rna editing, an essential post-transcriptional rna modification contributing to transcriptome and proteome diversification.

Transposable Elements

Transposable elements (tes) have profound effects on the structure, function and evolution of their host genomes.

Human Lung Cell Atlas

Examining the genomics, transcriptomics, proteomics, and metabolomics of the human lung at the single cell level will help build a single cell atlas of the lungs, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the lungs. Discover the latest research on the human cell lung atlas here.

Interferon Stimulated Genes

Interferon-stimulated gene products take on a number of diverse roles. Collectively, they are highly effective at resisting and controlling pathogens. Discover the latest research on interferon-stimulated genes here.

© 2020 Meta ULC. All rights reserved

Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats

BMC Genomics

Oct 30, 2010

Shoshana GreenbergerEli Eisenberg

PMID: 21029430

DOI: 10.1186/1471-2164-11-608

Abstract

Adenosine to inosine (A-to-I) RNA-editing is an essential post-transcriptional mechanism that occurs in numerous sites in the human transcriptome, mainly within Alu repeats. It has been shown to have consistent levels of editing across individuals in a few targets in the human brain and...read more

Mentioned in this Paper

Neuro-Oncological Ventral Antigen 2
Guanosine
Conserved Sequence
Untranslated Regions
Exons
Adenosine
Lung
Enzymes, antithrombotic
THOC5 gene
RNA, Double-Stranded

Similar Papers Found In These Feeds

Paper Details
References
  • References38
  • Citations20
/papers/consistent-levels-of-a-to-i-rna-editing-across/21029430