Constancy of uptake during the cell cycle in Escherichia coli

Biophysical Journal
H E Kubitschek

Abstract

Rates of uptake of several labeled compounds were measured during the cell cycle for three strains of Escherichia coli in balanced growth. Uptake rates were constant during more than the first two-thirds of the cycle, or reasonably so, for all of these compounds: glycine, leucine, glucose, acetate, phosphate, sulfate, and thymidine. When added de novo, uptake of glycine and leucine were not constant, but appeared to be proportional to mean cell volume. These results are in agreement with the finding that cell sizes increase linearly during most of the cell cycle for E. coli. They support the hypothesis, for cultures in balanced growth, that linear growth during the cell cycle is due to constant rates of uptake of all major growth factors. They also support the interpretation that uptake is limited by the presence of a constant number of functional binding or accumulation sites for these growth factors.

Citations

Feb 1, 1987·Archives of Microbiology·A Hart, C Edwards
Jan 1, 1993·Antonie van Leeuwenhoek·A L Koch
Jan 1, 1976·Bulletin of Mathematical Biology·T F Thingstad
Oct 1, 1989·Research in Microbiology·H E Kubitschek, S R Pai
Feb 1, 1992·Research in Microbiology·S R Pai, H E Kubitschek
Oct 1, 1977·Biophysical Journal·H E Kubitschek, R W Edvenson
Sep 26, 2013·Proceedings of the National Academy of Sciences of the United States of America·Yongjin SungMarc W Kirschner
May 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B H Shen, W Boos
Aug 10, 2012·Journal of Biological Dynamics·S F Ellermeyer, S S Pilyugin
Mar 1, 1971·Cell and Tissue Kinetics·H E Kubitschek
Mar 17, 1975·European Journal of Biochemistry·T Eremenko, P Volpe
Jul 11, 2009·Science·Amit TzurMarc W Kirschner
Oct 9, 2013·Journal of Theoretical Biology·Kristo AbnerRaivo Vilu
Jan 1, 1993·Critical Reviews in Microbiology·A L Koch
Dec 1, 1970·Journal of Bacteriology·S SilverK King
Jul 1, 1971·Journal of Bacteriology·H E Kubitschek, M L Freedman
Nov 1, 1981·Journal of Bacteriology·H E Kubitschek
Sep 1, 1988·Microbiological Reviews·A L Koch
Apr 1, 1984·Journal of Bacteriology·F S Archibald, M N Duong
Jun 1, 1973·Journal of Bacteriology·S Cooper, T Ruettinger
Jul 1, 1976·Journal of Bacteriology·H E Kubitschek, R V Claymen
Nov 1, 1986·Journal of Bacteriology·H E Kubitschek
Jan 1, 1990·Journal of Bacteriology·H E Kubitschek
Feb 1, 1971·Journal of Bacteriology·H E Kubitschek
Nov 30, 1982·Biochemical and Biophysical Research Communications·K S Planutis Evtodienko YuV
Oct 7, 1977·Journal of Theoretical Biology·S V Ho, M L Shuler
Feb 1, 1976·Journal of Theoretical Biology·P R Painter

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