Constant vs auto-continuous positive airway pressure in patients with sleep apnea hypopnea syndrome and a high variability in pressure requirement

Chest
André NosedaErnest Jann

Abstract

Auto-continuous positive airway pressure (CPAP) has been reported to have no more efficacy than constant CPAP in unselected patients with sleep apnea hypopnea syndrome (SAHS). The aim of this study was to evaluate patients judged to be good candidates for auto-CPAP because of a high within-night variability in pressure requirement. Single-blind, randomized, cross-over study (2 x 8 weeks) to compare auto-CPAP with constant CPAP. Outpatients with moderate-to-severe SAHS attending the chest clinic. Patients were equipped at home in the auto-CPAP mode (model GK418A; Malinckrodt; Nancy, France), using a 4- to 14-cm H(2)O pressure range. Those individuals having a high within-night variability in pressure requirement, assessed at the end of a 14-day run-in period, were included in the cross-over study. Auto-CPAP was compared with constant CPAP (according to a titration night in the sleep laboratory) in terms of compliance, efficacy on apneas (assessed from the pressure monitor), and sleepiness (assessed on the Epworth sleepiness scale). Of 90 consecutive patients with SAHS, 27 patients were selected for a within-night variability in pressure requirement exceeding a given threshold. After completion of the cross-over, 24 patients were...Continue Reading

References

Jul 8, 2000·The European Respiratory Journal·H TeschlerM Berthon-Jones
Jun 26, 2001·Psychiatry and Clinical Neurosciences·T HoriUNKNOWN Sleep Computing Committee of the Japanese Society of Sleep Research Society
Feb 15, 2002·The European Respiratory Journal·F LofasoB Louis

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Citations

Oct 3, 2008·BMC Pulmonary Medicine·Marta DrummondJosé A Marques
Sep 1, 2006·Neuropsychiatric Disease and Treatment·Craig A Hukins
Sep 2, 2010·Sleep Medicine Clinics·Omer Ahmed, Sairam Parthasarathy
May 22, 2010·Clinics in Chest Medicine·Neil Freedman
Feb 24, 2009·Sleep Medicine·A NosedaG Hoffmann
Sep 22, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Kenneth E Fleisher, Ana C Krieger
Jul 20, 2007·Sleep Medicine·J C MeuriceUNKNOWN ANTADIR "PPC" Working Group
May 29, 2007·Sleep Medicine·Adel BachourPaula K Maasilta
Apr 1, 2015·Revue des maladies respiratoires·E AntoneJ C Meurice
May 3, 2006·Respiratory Medicine·Yoshihiro KitaharaNobuoki Kohno
Aug 21, 2015·ERJ Open Research·Valentina IsettaRamon Farré
Oct 13, 2009·The Cochrane Database of Systematic Reviews·Ian Smith, Toby J Lasserson
Aug 20, 2019·Archives of Physical Medicine and Rehabilitation·Marnie GracoUNKNOWN COSAQ Investigators

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