PMID: 8953424Nov 1, 1996Paper

Constituents of Picralima nitida display pronounced inhibitory activities against asexual erythrocytic forms of Plasmodium falciparum in vitro

Journal of Ethnopharmacology
G FrançoisG Bringmann

Abstract

The antiplasmodial activities of organic and aqueous extracts from the West African plant Picralima nitida (Apocynaceae) were examined in an in vitro model, against asexual erythrocytic forms of Plasmodium falciparum. Root and leaf extracts of this species had never been examined before. Several extracts displayed considerable inhibitory activities. The highest activities were found in root, stem bark and fruit rind extracts, with IC50 values of 0.188, 0.545 and 1.581 micrograms/ml, respectively. The leaf and seed extracts generally yielded much lower activity or were completely inactive.

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Citations

Aug 21, 2013·BMC Complementary and Alternative Medicine·Laure Brigitte Mabeku KouitcheuJacques Kouam
Mar 1, 2007·Pakistan Journal of Biological Sciences : PJBS·A C IgboasoiyiG Ubam
Jan 1, 2006·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·Jean BickiiEtienne Tsamo
Dec 18, 2001·Movement Disorders : Official Journal of the Movement Disorder Society·E D Louis
Apr 5, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Stephen T LacmataJean-Marie Pages
Jan 20, 2007·Journal of Ethnopharmacology·Jude E OkokonH O C Mbagwu
Nov 26, 2010·Journal of Ethnopharmacology·J O Adebayo, A U Krettli
Jan 15, 2014·Asian Pacific Journal of Tropical Medicine·Osayemwenre ErharuyiPeter Langer
Oct 9, 1999·Clinical Microbiology Reviews·M M Cowan

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