Constitutive activation of the jasmonate signaling pathway enhances the production of secondary metabolites in tomato

FEBS Letters
Hui ChenGregg A Howe

Abstract

The phytohormone jasmonic acid (JA) regulates the synthesis of secondary metabolites in a wide range of plant species. Here, we show that exogenous methyl-JA (MeJA) elicits massive accumulation of caffeoylputrescine (CP) in tomato leaves. A mutant (jai1) that is defective in jasmonate perception failed to accumulate CP in flowers and MeJA-treated leaves. Conversely, a transgenic tomato line (called 35S::PS) that exhibits constitutive JA signaling accumulated high levels of leaf CP in the absence of jasmonate treatment. RNA blot analysis showed that genes encoding enzymes in the phenylpropanoid and polyamine pathways for CP biosynthesis are upregulated in MeJA-treated wild-type plants and in untreated 35S::PS plants. These results indicate that CP accumulation in tomato is tightly controlled by the jasmonate signaling pathway, and provide proof-of-concept that the production of some plant secondary metabolites can be enhanced by transgenic manipulation of endogenous JA levels.

References

Jan 17, 1995·Proceedings of the National Academy of Sciences of the United States of America·C P ConstabelC A Ryan
Oct 11, 1994·Proceedings of the National Academy of Sciences of the United States of America·B McGurlC A Ryan
Oct 29, 1996·Proceedings of the National Academy of Sciences of the United States of America·D R BergeyC A Ryan
Apr 5, 2001·Proceedings of the National Academy of Sciences of the United States of America·H S SeoY D Choi
May 4, 2001·Trends in Plant Science·J MemelinkJ W Kijne
May 24, 2001·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Y OguraH Iwamura
Oct 11, 2001·Proceedings of the National Academy of Sciences of the United States of America·A StintziE E Farmer
Aug 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·V R Franceschi, H D Grimes
Mar 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·H GundlachM H Zenk
Sep 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·M Orozco-CardenasC A Ryan
Mar 5, 2002·The Plant Journal : for Cell and Molecular Biology·Anders B JensenJohn Mundy
Apr 18, 2002·Proceedings of the National Academy of Sciences of the United States of America·Lei LiGregg A Howe
Sep 12, 2002·Annual Review of Plant Biology·Ivo Feussner, Claus Wasternack
Jun 27, 2003·Proceedings of the National Academy of Sciences of the United States of America·Alain GoossensKirsi-Marja Oksman-Caldentey
Sep 2, 2003·Proceedings of the National Academy of Sciences of the United States of America·Clarence A Ryan, Gregory Pearce
Aug 24, 2004·The Journal of Biological Chemistry·Hui ChenGregg A Howe
Apr 6, 2005·The Plant Journal : for Cell and Molecular Biology·Srinivasa Rao UppalapatiCarol L Bender
Apr 26, 2005·Biotechnology Advances·Jian ZhaoRobert Verpoorte
Jun 9, 2005·Current Opinion in Plant Biology·Anthony L Schilmiller, Gregg A Howe

❮ Previous
Next ❯

Citations

Sep 8, 2009·Journal of Experimental Botany·Marcelo Lattarulo CamposLázaro Eustáquio Pereira Peres
Sep 5, 2012·Journal of Experimental Botany·Lihong LiuQiaomei Wang
Feb 18, 2012·Plant Physiology·Stephan GoetzBettina Hause
Feb 23, 2013·International Journal of Molecular Sciences·Lina García-MierIrineo Torres-Pacheco
Apr 15, 2014·Insect Biochemistry and Molecular Biology·Marco Herde, Gregg A Howe
Jul 12, 2007·Proceedings of the National Academy of Sciences of the United States of America·Pramod Kaitheri KandothJohannes W Stratmann
Dec 15, 2010·Plant Physiology and Biochemistry : PPB·Alma R Altúzar-MolinaS M Teresa Hernández-Sotomayor
Mar 2, 2010·Phytochemistry·Jonathan Negrel, Francine Javelle
Jul 25, 2009·Journal of Proteomics·Sophie AlvarezSixue Chen
Jun 21, 2013·The New Phytologist·Lauren A Du Fall, Peter S Solomon
Jan 27, 2011·The Plant Journal : for Cell and Molecular Biology·Sarah R HindJohannes W Stratmann
Feb 24, 2015·The New Phytologist·Ricardo A R MachadoMatthias Erb
May 24, 2015·Plant Physiology and Biochemistry : PPB·Maissa Ben-JabeurWalid Hamada
Mar 17, 2011·Plant Signaling & Behavior·Yu Hua Wang, Helen R Irving
Oct 18, 2012·Plant Signaling & Behavior·Rafael Jorge León MorcilloJosé M García Garrido
Jan 13, 2015·Molecular Plant·Lihong LiuQiaomei Wang
Jun 4, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marjorie Reyes-DíazAlejandra Ribera-Fonseca
Jan 25, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yingchao XuKarl W K Tsim
Mar 15, 2018·Annual Review of Plant Biology·Gregg A HoweAbraham J Koo
Sep 1, 2017·Molecular Plant-microbe Interactions : MPMI·Cristina RiojaVojislava Grbic
Jan 29, 2014·Archiv der Pharmazie·Abdollah Ghasemi PirbaloutiKeykavous Parang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.