PMID: 11331528May 2, 2001Paper

Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse

The Journal of Comparative Neurology
C L ArmstrongR Hawkes

Abstract

Immunohistochemistry and in situ hybridization have been used to survey constitutive heat shock protein (HSP)25 expression in the brain and spinal cord of the developing and adult mouse. The data reveal both transient and sustained patterns of expression and demonstrate robust differences between mice and rats. During development, HSP25 is transiently expressed in neurons of the inferior colliculus, various thalamic subnuclei, and the majority of Purkinje cells in the cerebellum. Sustained expression into adulthood is seen in neurons of the cranial nerve nuclei, spinal cord motoneurons, median preoptic nucleus, and a subset of Purkinje cells. Differences in HSP25 expression between adult rats and mice include the somatic motor nuclei innervating the extraocular muscles, which are HSP25 immunoreactive only in the rat. Similar differences in HSP25 expression are seen during the development of the inferior colliculus, thalamus, and cerebellum, where expression is restricted to mice.

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Citations

Aug 7, 2009·The Journal of Biological Chemistry·Meyer J FriedmanXiao-Jiang Li
Dec 3, 2005·The Cerebellum·Emmanuelle Bitoun, Kay Elizabeth Davies
Jun 15, 2011·Molecular and Cellular Biology·Juhi OjhaAnil G Cashikar
Jun 9, 2006·Expert Review of Anticancer Therapy·Michael W Graner, Darell D Bigner
Aug 6, 2010·Progress in Neurobiology·R Anne StetlerJun Chen
Jan 11, 2011·Journal of Neurochemistry·Maria Dolores LedesmaEdward H Schuchman
Dec 7, 2013·Neural Plasticity·Hermina Nedelescu, Mohamed Abdelhack
Dec 24, 2004·Biochimica Et Biophysica Acta·Kenneth S Kosik, Hideki Shimura
May 7, 2009·Experimental Neurology·Shannon L MacauleyMark S Sands
Feb 3, 2007·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Anne Mulligan TuttleJohn J Heikkila
Dec 10, 2003·The Journal of Biological Chemistry·Olivier DuvergerMichel Morange
Sep 7, 2004·The Journal of Comparative Neurology·Erin L HawkesDavid B Clarke
Sep 28, 2005·Neurochemical Research·Stéphane WoerlyAraceli Espinosa-Jeffrey
Jan 4, 2012·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Noelia García-LaxFaustino Marín

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