PMID: 7546567DOI: 10.1016/s0167-7799(00)88997-0Oct 1, 1995Paper
Constrained peptides as binding entities
Trends in Biotechnology
Robert C Ladner
Abstract
Displaying proteins and peptides on genetic packages and selecting packages that display high-affinity binders allows large numbers of peptidyl compounds to be tested for binding to targets. Phage-displayed libraries of unstructured peptides (UPs) have yielded binders for some targets, but not for many others. Therefore, more attention is being paid to peptidyl compounds that have varied regions that are subject to conformational constraint.
References
Jan 14, 1992·Biochemistry·A M de VosA A Kossiakoff
Mar 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·B L RobertsR C Ladner
Jul 27, 1990·Science·J K Scott, G P Smith
Nov 5, 1991·Biochemistry·R J Leatherbarrow, H J Salacinski
Oct 30, 1990·Biochemistry·T R HynesA A Kossiakoff
Jul 27, 1990·Science·J J DevlinP E Devlin
Aug 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·S E CwirlaW J Dower
Jan 1, 1987·Cold Spring Harbor Symposia on Quantitative Biology·T E Creighton, I G Charles
Dec 20, 1988·Gene·S F Parmley, G P Smith
Nov 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·M BalassS Fuchs
Feb 1, 1994·The Journal of Cell Biology·E KoivunenE Ruoslahti
Nov 18, 1994·Science·S FengS L Schreiber
Jan 20, 1995·Science·T Clackson, J A Wells
Apr 1, 1993·Current Opinion in Immunology·D P Lane, C W Stephen
Jun 15, 1993·Gene·C PinillaR A Houghten
May 1, 1994·Trends in Biotechnology·T Clackson, J A Wells
Jul 19, 1994·Proceedings of the National Academy of Sciences of the United States of America·R J GoodsonS Rosenberg
Dec 5, 1993·Journal of Molecular Biology·K D BerndtK Wüthrich
Jun 15, 1993·Gene·M A McLaffertyW Markland
Jun 15, 1993·Gene·G P SmithJ E Ladbury
Jun 15, 1993·Gene·B K KayD M Fowlkes
Mar 1, 1995·Bio/technology·E KoivunenE Ruoslahti
Feb 19, 2010·Protein Engineering, Design & Selection : PEDS·K PershadJ McCafferty
❮ Previous
Next ❯
Citations
Feb 19, 2000·Biopolymers·M SavianoC Toniolo
Apr 13, 2001·Journal of Molecular Recognition : JMR·K WelfleH Welfle
Jul 3, 2002·Journal of Peptide Science : an Official Publication of the European Peptide Society·Mario RainaldiGiorgio Cavicchioni
Aug 1, 1996·Journal of Protein Chemistry·T Kikuchi
Nov 5, 2002·Clinical Biochemistry·Hassan M E Azzazy, W Edward Highsmith
Oct 29, 1998·Journal of Chromatography. B, Biomedical Sciences and Applications·T BurnoufM Radosevich
Oct 11, 2003·Biotechnology Advances·I Benhar
Aug 1, 1997·Current Opinion in Biotechnology·T Kieber-EmmonsM I Greene
Aug 1, 1997·Current Opinion in Structural Biology·P A Nygren, M Uhlén
Sep 22, 2001·The Journal of Steroid Biochemistry and Molecular Biology·F Hoppe-SeylerK Butz
Sep 6, 2002·Bioorganic & Medicinal Chemistry·Manju BalaSantosh Pasha
Aug 31, 2001·Journal of Biotechnology·J CollinsM Szardenings
Mar 26, 2011·Journal of Chemical Information and Modeling·Fergal J DuffyAnthony J Chubb
Nov 17, 2009·Nature Chemical Biology·Takashi KawakamiHiroaki Suga
Jan 20, 2004·Cell Research·Jie CaoZhong tian Qi Zt
Oct 29, 2000·European Journal of Biochemistry·N WolffS Zinn-Justin
Jun 1, 2000·Proceedings of the National Academy of Sciences of the United States of America·K ButzF Hoppe-Seyler
Apr 18, 1998·Proceedings of the National Academy of Sciences of the United States of America·K N MorrisL Gold
Feb 28, 1998·Nucleic Acids Research·M R AbediA Kamb
Feb 25, 2010·Protein Engineering, Design & Selection : PEDS·Toni HoffmannPaul Ko Ferrigno
May 28, 2011·Protein Engineering, Design & Selection : PEDS·Lukas Kurt Josef StadlerPaul Ko Ferrigno
Jan 1, 1997·Annual Review of Biophysics and Biomolecular Structure·H B Lowman
May 31, 2008·BMC Structural Biology·Karin NoyChen Keasar
Oct 20, 2005·Journal of Bioscience and Bioengineering·Fumiaki UchiyamaNoritaka Tokui
Mar 21, 2001·Pharmacogenomics·R C Ladner
Mar 25, 2011·Future Medicinal Chemistry·Jody M Mason
Aug 2, 2014·PloS One·Tetsuya KadonosonoShinae Kizaka-Kondoh
Sep 20, 2012·Journal of Nucleic Acids·Keisuke Fukunaga, Masumi Taki
Jun 19, 2007·Journal of Molecular Biology·Sabine GilchHermann M Schätzl
Mar 17, 2006·Biochemical and Biophysical Research Communications·Cédric BèsThierry Chardès
Sep 6, 2005·Journal of Molecular Biology·Robbie WoodmanPaul Ko Ferrigno
May 12, 2005·The Journal of Peptide Research : Official Journal of the American Peptide Society·M CrismaC Toniolo
Jun 15, 2005·Expert Opinion on Biological Therapy·Corina BorghoutsBernd Groner
Oct 1, 2006·Expert Opinion on Drug Discovery·Paul M WattWayne R Thomas
Feb 1, 2003·Science in China. Series C, Life Sciences·Zhongcai MaZhongtian Qi
Mar 1, 2011·Hormone Molecular Biology and Clinical Investigation·Hannah SchönebergerBernd Groner
May 5, 2004·Chemistry & Biology·Kevin M MarksGarry P Nolan
Apr 9, 2013·Journal of the American Chemical Society·Shiyu ChenChristian Heinis
Mar 25, 2005·Environment International·S W ZhaoZ C Hua
Jul 9, 1999·Proteins·S D NuttallP J Hudson
Jun 30, 2000·Journal of Molecular Biology·M B ZwickJ K Scott
Dec 31, 2002·Journal of Receptor and Signal Transduction Research·Oliver Hartley
Apr 28, 2009·Cellular and Molecular Life Sciences : CMLS·Sabine Gilch, Hermann M Schätzl
Jul 30, 2015·Biomaterials Science·Duhwan LeeWon Jong Kim
Mar 28, 2013·International Journal of Molecular Sciences·Andrea ConidiDanny Huylebroeck
Jul 29, 2004·Biotechnology and Bioengineering·Brian D KelleyJames Booth
Feb 18, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Thomas LindnerWalter Mier
Apr 28, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Guillaume CastelNoël Tordo
Dec 29, 2006·Chemistry & Biodiversity·Cristiano ChiarabelliPier Luigi Luisi
Feb 8, 2019·Molecular Biotechnology·Mouldy Sioud
❮ Previous
Next ❯
Related Concepts
Related Feeds
Bacteriophage: Phage Therapy
Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.
Related Papers
Proteins
Bostjan JapeljRoman Jerala
Molecular Immunology
Jonas PerssonMats Ohlin
Cellular and Molecular Life Sciences : CMLS
B KlevenzF Hoppe-Seyler
PloS One
Takahiro KuchimaruShinae Kizaka-Kondoh
Green fluorescent protein as a scaffold for intracellular presentation of peptides
(opens in new tab)Nucleic Acids Research
M R AbediA Kamb