Constraints on muscular performance: trade-offs between power output and fatigue resistance

Proceedings. Biological Sciences
Robbie S Wilson, Rob S James

Abstract

An important functional and evolutionary constraint on the physical performance of vertebrates is believed to be the trade-off between speed and endurance capacity. However, despite the pervasiveness of physiological arguments, most studies have found no evidence of the trade-off when tested at the whole-animal level. We investigated the existence of this trade-off at the whole-muscle level, the presumed site of this physiological conflict, by examining inter-individual variation in both maximum power output and fatigue resistance for mouse extensor digitorum longus (EDL) muscle using the work-loop technique. We found negative correlations between several measures of in vitro maximum power output and force production with fatigue resistance for individual mouse EDL muscles, indicating functional trade-offs between these performance parameters. We suggest that this trade-off detected at the whole-muscle level has imposed an important constraint on the evolution of vertebrate physical performance.

References

Jan 1, 1994·Annual Review of Physiology·T Garland, P A Carter
Jan 1, 1993·Annual Review of Physiology·R K Josephson
May 1, 1996·Research in Veterinary Science·G Goldspink
Aug 26, 2000·Progress in Biophysics and Molecular Biology·R Bottinelli, C Reggiani
Feb 15, 2002·Nature·Raoul Van DammePeter Aerts
Oct 2, 2002·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·M A Ashley-Ross, J U Barker

❮ Previous
Next ❯

Citations

Nov 29, 2015·Evolution; International Journal of Organic Evolution·Jeffrey Scales, Marguerite Butler
Jan 22, 2014·Journal of Evolutionary Biology·E LombaertT Guillemaud
Aug 17, 2010·Behavioural Processes·William S Helton
Jun 3, 2016·The Journal of Experimental Biology·Frank SeebacherZhongning Yan
Oct 7, 2016·The Journal of Experimental Biology·Henry C Astley
Apr 4, 2019·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·Simon P LailvauxThomas M Houslay
Aug 5, 2017·Proceedings. Biological Sciences·Vincent Careau, Robbie S Wilson
Apr 16, 2020·The Journal of Experimental Biology·Daniel J TobianskyMatthew J Fuxjager
Jul 5, 2017·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Frank Seebacher, Jens Krause
Sep 2, 2017·Integrative and Comparative Biology·Vincent Careau, Robbie S Wilson
Aug 2, 2020·The Journal of Experimental Biology·Stephanie A RossJames M Wakeling
Dec 18, 2015·The Journal of Experimental Biology·Frank SeebacherRob S James
Mar 6, 2007·The Journal of Experimental Biology·Rob S JamesAnthony Herrel

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.