Construct and concurrent validation of the MG-QOL15 in the practice setting

Muscle & Nerve
Ted M Burnsmg composite and mg-qol15 study group

Abstract

Health-related quality of life (HRQOL) estimates can play an important role in patient care by providing information about the patient's perception of impairment and disability and the degree to which the patient tolerates disease manifestations. The 15-item myasthenia gravis quality of life scale (MG-QOL15) is an HRQOL evaluative instrument specific to patients with myasthenia gravis (MG) that was designed to be easy to administer and interpret. In this multicenter study we demonstrate the construct validity of the MG-QOL15 in the practice setting. To assess the construct validity, score distributions were examined for test items in different MG patient groups that represent the clinical spectrum of the disease. For example, patients in remission more frequently scored test items as normal than did patients in other groups. Patients with lower (better) MG composite scores also more frequently scored items as normal than did patients with higher (worse) scores. There was also appropriate correlation between the MG-QOL15 and the other MG-specific scales studied. The study findings shed light on what troubles MG patients. The MG-QOL15 has construct validity in the clinical practice setting and represents an efficient and valuable...Continue Reading

References

Jan 1, 1990·Journal of Clinical Epidemiology·L S EbbesenN B Oldridge
Sep 1, 1984·Journal of Medical Ethics·K C Calman
Nov 1, 1995·Social Science & Medicine·M Farquhar
Jul 21, 1998·Annals of the New York Academy of Sciences·R J BarohnW W Bryan
May 5, 1999·Neurology·G I WolfeR J Barohn
Sep 18, 2002·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·L PaduaP Tonali
Nov 1, 2003·Annals of the New York Academy of Sciences·Donald B SandersJanice M Massey
Jun 27, 2008·Clinical Pharmacology and Therapeutics·L B BurkeA M Trentacosti
Jul 22, 2008·Muscle & Nerve·Ted M BurnsUNKNOWN Muscle Study Group
Aug 13, 2008·Muscle & Nerve·Larry L MullinsUNKNOWN Muscle Study Group
Nov 20, 2008·Muscle & Nerve·Ted M BurnsUNKNOWN Muscle Study Group

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Citations

Oct 15, 2013·Muscle & Nerve·Farah SeedatMichael R Rose
Feb 16, 2019·Muscle & Nerve·Srikanth MuppidiUNKNOWN Regain Study Group
Nov 18, 2010·Muscle & Nerve·Ted M BurnsUNKNOWN MG Composite and MG-OL15 Study Group
Jul 19, 2012·Muscle & Nerve·Elena Hernández Martínez-LapiscinaIvonne Jericó Pascual
Jul 19, 2012·Muscle & Nerve·Masayuki MasudaNorihiro Suzuki
Dec 19, 2013·Arquivos de neuro-psiquiatria·Aline Mansueto MourãoAntonio Lucio Teixeira
Feb 19, 2014·Muscle & Nerve·Kimiaki UtsugisawaNorihiro Suzuki
Oct 27, 2017·Seminars in Ophthalmology·Kerr BroganKevin Crofts
May 23, 2015·The International Journal of Neuroscience·Yongxiang YangZhuyi Li
Dec 3, 2016·Arquivos de neuro-psiquiatria·Ezequiel Fernandes OliveiraLuis Vicente Franco Oliveira
Feb 22, 2017·Journal of Clinical Neuromuscular Disease·Srikanth Muppidi
Sep 26, 2020·Dementia & Neuropsychologia·Annelise AyresMaira Rozenfeld Olchik
Mar 9, 2017·Muscle & Nerve·Ellen StrijbosJan J Verschuuren
Sep 29, 2019·Annals of Clinical and Translational Neurology·Shruti M RajaJeffrey T Guptill
May 13, 2020·Neuro-ophthalmology·Sui Hsien WongCarolina Barnett
Oct 18, 2016·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·John A MorrenRobert W Shields
Jul 27, 2017·Arquivos de neuro-psiquiatria·Ezequiel Fernandes OliveiraLuis Vicente Franco Oliveira
Oct 28, 2020·Logopedics, Phoniatrics, Vocology·Annelise AyresMaira Rozenfeld Olchik
Mar 25, 2019·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Henning AndersenUNKNOWN REGAIN Study Group
May 3, 2019·Nature Reviews. Disease Primers·Nils Erik GilhusJan J G M Verschuuren
May 29, 2019·Journal of Clinical Neuromuscular Disease·Audra N BoscoeGary R Cutter
Dec 23, 2019·BMC Neurology·Elizabeth Dansie BacciAudra N Boscoe
Jul 24, 2010·Current Opinion in Neurology·Maria Elena Farrugia, Angela Vincent
Feb 18, 2021·Journal of Clinical Neuromuscular Disease·Sarah YangSrikanth Muppidi
Feb 20, 2021·Muscle & Nerve·Devin E PriorPartha S Ghosh
Oct 16, 2010·Current Opinion in Ophthalmology

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