PMID: 8614638Apr 1, 1996Paper

Construction of a chromosome specific library of human MARs and mapping of matrix attachment regions on human chromosome 19

Nucleic Acids Research
Lev G NikolaevEugene D Sverdlov

Abstract

Using a novel procedure a representative human chromosome 19-specific library was constructed of short sequences, which bind preferentially to the nuclear matrix (matrix attachment regions, or MARs). Judging by 20 clones sequenced so far, the library contains > 50% of human inserts, about 90% of which are matrix-binding by the in vitro test. Computer analysis of sequences of eight human MARs did not reveal any significant homologies with the EMBL Nucleotide Data Base entries as well as between MARs themselves. Eight MARs were assigned to individual positions on the chromosome 19 physical map. The library constructed can serve as a good source of MAR sequences for comparative analysis and classification and for further chromosome mapping of MARs as well.

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Citations

Aug 1, 1997·Journal of Molecular Neuroscience : MN·A A Gimelbrant, T S McClintock
Mar 26, 2003·Proceedings of the National Academy of Sciences of the United States of America·Mario A PennellaDavid P Giedroc
Apr 1, 1997·Nucleic Acids Research·G B SinghS A Krawetz
Feb 5, 2008·Molekuliarnaia biologiia·S B AkopovL G Nikolaev
Mar 6, 2007·BMC Bioinformatics·Kenneth EvansLorenz Wernisch
Feb 13, 2001·FEBS Letters·J Yamamura, K Nomura
Jun 26, 2015·Digestive Diseases and Sciences·Zheng ChenZekuan Xu
Mar 17, 2020·Journal of Child and Adolescent Mental Health·Renate Gericke, Katherine Bain
Oct 25, 2002·Family Process·Kasia Kozlowska, Lesley Hanney
Mar 25, 2005·Bioorganicheskaia khimiia·A V SassE D Sverdlov

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