PMID: 11920539Mar 29, 2002Paper

Construction of the Chinese University Prognostic Index for hepatocellular carcinoma and comparison with the TNM staging system, the Okuda staging system, and the Cancer of the Liver Italian Program staging system: a study based on 926 patients

Cancer
Thomas W T LeungPhilip J Johnson

Abstract

The current TNM staging system for patients with hepatocellular carcinoma (HCC) does not include liver function parameters and does not provide a precise prognosis for patients in different risk groups. The objectives of this study were to construct a new prognostic index for patients with hepatocellular carcinoma, the Chinese University Prognostic Index (CUPI), and to compare it with existing staging systems in terms of their ability to classify patients into different risk group. From 1996 to 1998, 926 ethnic Chinese patients who were diagnosed with HCC (mainly hepatitis B-associated) at a single institution were recruited prospectively into this study. A multivariate analysis on 19 patient characteristics was performed using a Cox regression model to identify independent prognostic factors. Weights were derived from the regression coefficients of various factors to construct the CUPI. Patients were classified according to different staging systems. Survival curves were plotted with the Kaplan-Meier method and were compared by using a log-rank test. Both the TNM staging system and the Okuda staging system had prognostic significance, but the significance was lower for the Cancer of the Liver Italian Program (CLIP) prognostic ...Continue Reading

References

Aug 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Y AkashiK Inoue
Oct 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·X CalvetJ Rodés
Oct 31, 1997·Lancet·S D Taylor-RobinsonH C Thomas
Sep 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Mar 11, 1999·The New England Journal of Medicine·H B El-Serag, A C Mason
Jun 5, 1999·Science·B R BloomJ D Sachs

❮ Previous
Next ❯

Citations

Aug 19, 2003·Seminars in Surgical Oncology·Leslie H Sobin
Apr 12, 2011·Abdominal Imaging·Irene Bargellini
Sep 27, 2012·Seminars in Immunopathology·Alessio Aghemo, Massimo Colombo
Dec 21, 2005·Journal of Hepato-biliary-pancreatic Surgery·Justin M Burns, Frederick L Greene
Oct 19, 2006·Journal of Gastroenterology·Iwao IkaiUNKNOWN Liver Cancer Study Group of Japan
Jul 12, 2008·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Franck BonnetainLaurent Bedenne
Nov 1, 2011·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Shuang WeiZhiyong Huang
May 5, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ming-Chin YuMiin-Fu Chen
Apr 7, 2004·Current Oncology Reports·Jill Allen, Alan Venook
Sep 4, 2008·Current Oncology Reports·Ghassan K Abou-Alfa, Alan P Venook
Mar 11, 2005·Best Practice & Research. Clinical Gastroenterology·Mindie H Nguyen, Emmet B Keeffe
Mar 11, 2005·Best Practice & Research. Clinical Gastroenterology·Philip J Johnson, Lucinda J Billingham
Dec 16, 2003·Journal of Hepatology·Umberto CilloDavide Francesco D'Amico
Feb 20, 2003·Journal of Hepatology·Josep M Llovet, Michel Beaugrand
Jul 8, 2010·International Journal of Clinical and Experimental Medicine·Gabriele KirchnerClaus Hellerbrand
Nov 9, 2010·Journal of Psychosocial Oncology·Chrishanthy ThambyrajahCarrie Llewellyn
Jun 9, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J O LeeY J Bang
Jun 5, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G DanieleM Pirisi
May 15, 2008·Journal of the National Cancer Institute·Josep M LlovetUNKNOWN Panel of Experts in HCC-Design Clinical Trials
Feb 11, 2005·Current Opinion in Gastroenterology·Jorge A Marrero
Apr 9, 2008·The Cancer Journal·John P DuffyRonald W Busuttil
Sep 13, 2005·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Massimo Colombo
Oct 16, 2004·Journal of Gastroenterology and Hepatology·Kazufumi Dohmen
Jul 19, 2008·Journal of Gastroenterology and Hepatology·Yeon Seok SeoHo Sang Ryu
Aug 14, 2008·Journal of Gastroenterology and Hepatology·Brian I CarrRobert A Branch
Aug 28, 2010·Journal of Gastroenterology and Hepatology·Brian I CarrRobert A Branch
Jul 16, 2011·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·Yongyut Sirivatanauksorn, Chutwichai Tovikkai
May 12, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Fidel-David Huitzil-MelendezGhassan K Abou-Alfa
Aug 4, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Melanie B ThomasAlan Venook
Jun 7, 2006·Chemical & Pharmaceutical Bulletin·Sheng-Jun DaiLi Shen
Aug 2, 2007·Chemical & Pharmaceutical Bulletin·Sheng-Jun DaiLi Shen
Feb 2, 2008·Chemical & Pharmaceutical Bulletin·Sheng-Jun DaiLi Shen
Apr 2, 2009·Chemical & Pharmaceutical Bulletin·Yan RenSheng-Jun Dai

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.