Consumption of fish from a contaminated lake strongly affects the concentrations of polybrominated diphenyl ethers and hexabromocyclododecane in serum

Molecular Nutrition & Food Research
Cathrine ThomsenGeorg Becher

Abstract

Very high concentrations of polybrominated diphenyl ethers (PBDE) have been reported in fish from Lake Mjøsa in Norway. This study was performed to examine the serum concentrations of PBDE and hexabromocyclododecane (HBCD) in consumers of fish from this lake and to investigate possible relationships between serum concentrations, self-reported fish intake and calculated total dietary PBDE exposure. Serum concentrations of the sum of the seven PBDE (BDE-28, 47, 99, 100, 153, 154 and 183) were significantly higher than those of a reference group of Norwegians eating only food with background levels of contamination (medians: 18 ng/g lipids men, 8.4 ng/g lipids women). The median dietary intake of Sum 7 PBDE was 2549 ng/day (30 ng/kg body weight/day), the highest dietary intake of PBDE reported. The contribution from fish caught from the contaminated lake comprised 98.7% of the total dietary exposure. For men, serum levels of PBDE were strongly correlated with the calculated dietary exposure, except for BDE-209. This suggests that sources other than the diet are important for human BDE-209 exposure. The median serum HBCD concentration was 4.1 and 2.6 ng/g lipids for men and women, respectively, and was also found to be associated w...Continue Reading

References

Mar 17, 2001·Environmental Health Perspectives·P O DarnerudM Viluksela
May 16, 2001·Environmental Science & Technology·A SjödinC Ostman
Oct 24, 2001·Environmental Health Perspectives·P ErikssonA Fredriksson
May 10, 2002·Chemosphere·Cynthia A de Wit
May 2, 2003·Journal of Agricultural and Food Chemistry·A BocioC Casas
Jul 10, 2003·Environment International·Per Ola Darnerud
Dec 31, 2003·Environmental Health Perspectives·Linda S Birnbaum, Daniele F Staskal
May 1, 2004·Environmental Science & Technology·Ingrid VivesDamià Barceló
May 1, 2004·Environmental Science & Technology·Stuart HarradRobert Baker
Jun 16, 2004·Environment International·Hannu KivirantaTerttu Vartiainen
Jun 24, 2004·Environmental Science & Technology·Ling Yan Zhu, Ronald A Hites
May 6, 2005·Environmental Science & Technology·Kaj ThuressonKristina Jakobsson
Aug 9, 2005·Environmental Science & Technology·Heather A Jones-OtazoBryony Wilford
Oct 6, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Adrian Covaci, Stefan Voorspoels
Dec 7, 2005·Environmental Health Perspectives·Kimberly B MorlandDonald G Patterson
Jul 13, 2006·Environmental Science & Technology·Adrian CovaciJacob De Boer
Sep 19, 2006·Environment International·Stefan VoorspoelsPaul Schepens
Sep 21, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Leo T M van der VenJosephus G Vos
Oct 7, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Cathrine ThomsenGeorg Becher
Apr 3, 2007·Environmental Science & Technology·Nerissa WuThomas F Webster

❮ Previous
Next ❯

Citations

Mar 11, 2011·Journal of Toxicology and Environmental Health. Part a·Vidar BergErik Ropstad
Jul 31, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Anne DreiemRichard F Seegal
Feb 22, 2012·Toxicological Sciences : an Official Journal of the Society of Toxicology·Veronica M MillerRichard F Seegal
Jun 1, 2012·Environmental Health Perspectives·Arnold SchecterLinda S Birnbaum
Jun 15, 2016·Journal of Immunotoxicology·Sharif Anisuzzaman, Margaret M Whalen
Oct 4, 2012·Environment International·Helen Engelstad KvalemHelle K Knutsen
Jul 10, 2012·Environment International·Hong-Sheng WangChris Kong-Chu Wong
Jun 11, 2011·Journal of Hazardous Materials·Hong-Sheng WangMing-Hung Wong
Mar 29, 2011·International Journal of Hygiene and Environmental Health·Lesa L Aylward, Sean M Hays
May 18, 2010·International Journal of Hygiene and Environmental Health·Marie FrederiksenLisbeth E Knudsen
Sep 29, 2009·International Journal of Hygiene and Environmental Health·Teck-Wai KohHow-Ran Chao
Apr 11, 2008·Environment International·Laurence RoosensAdrian Covaci
Mar 5, 2008·International Journal of Andrology·P O Darnerud
Jul 12, 2008·Molecular Nutrition & Food Research·Michael HabermeyerGerhard Eisenbrand
Feb 1, 2011·Molecular Nutrition & Food Research·Helle K KnutsenCathrine Thomsen
Sep 29, 2015·International Journal of Hygiene and Environmental Health·H FrommeW Völkel
Apr 14, 2016·International Journal of Hygiene and Environmental Health·Hermann FrommeWolfgang Völkel
Sep 26, 2013·The Science of the Total Environment·Dorothea F K RawnCynthia G Goodyer
Dec 3, 2013·Environment International·Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Oct 4, 2016·International Journal of Hygiene and Environmental Health·Gabriele Leng, Wolfgang Gries
Jun 24, 2009·Environmental Science & Technology·Laurence RoosensAdrian Covaci
Dec 17, 2008·Journal of Agricultural and Food Chemistry·Yingxin YuJiamo Fu
Dec 11, 2014·Environmental Science & Technology·Leena M O SahlströmPer Ola Darnerud

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.