Consumption of flavonoid-rich fruits and risk of CHD: a prospective cohort study.

The British Journal of Nutrition
Yiyi YangJapan Public Health Center-based Prospective Study Group

Abstract

Although the association between fruit consumption and CHD risk has been well studied, few studies have focused on flavonoid-rich fruits (FRF), in particular strawberries and grapes. We aimed to verify the association of total and specific FRF consumption with risk of CHD by a large prospective cohort study. A total of 87 177 men and women aged 44-75 years who were free of CVD and cancer at study baseline were eligible for the present analysis. FRF consumption was assessed using a FFQ. Cox proportional hazards regression models were used to estimate the hazard ratios (HR) of CHD in relation to FRF consumption with adjustment for potential risk factors and confounders. During a mean follow-up of 13·2 years, we identified 1156 incident CHD cases. After full adjustment for covariates including demographics, lifestyles and dietary factors, the HR were 0·93 (95 % CI 0·77, 1·11), 0·91 (95 % CI 0·75, 1·11), 0·84 (95 % CI 0·67, 1·04) and 0·78 (95 % CI 0·62, 0·99) for the second, third, fourth and fifth quintiles compared with the lowest quintile of FRF consumption. Regarding specific fruits, we observed a significant inverse association for citrus fruit consumption and a borderline inverse association for strawberry consumption, while ...Continue Reading

References

Jun 1, 1994·Free Radical Biology & Medicine·Y HanasakiS Fukui
Jan 1, 1997·Advances in Pharmacology·L G Korkina, I B Afanas'ev
Feb 13, 2001·The Journal of Clinical Investigation·Y Yamamoto, R B Gaynor
Aug 7, 2002·Circulation·Joseph A Vita, John F Keaney
Apr 29, 2004·The American Journal of Clinical Nutrition·Claudine ManachLiliana Jiménez
Apr 22, 2005·The New England Journal of Medicine·Göran K Hansson
Mar 9, 2007·The American Journal of Clinical Nutrition·Pamela J MinkDavid R Jacobs
Mar 24, 2007·American Journal of Epidemiology·Jennifer LinJoAnn E Manson
Oct 2, 2007·Journal of the American College of Nutrition·Howard D SessoJulie E Buring
Sep 21, 2010·European Heart Journal·Christian HeissMalte Kelm
Jan 6, 2012·The American Journal of Clinical Nutrition·Marjorie L McCulloughJohanna T Dwyer
Sep 18, 2012·Vascular Pharmacology·Andreas LeihererHeinz Drexel
Nov 1, 2013·The American Journal of Clinical Nutrition·Davide GrassiClaudio Ferri
Jan 24, 2014·Journal of Agricultural and Food Chemistry·Francesca GiampieriMaurizio Battino
Apr 1, 2014·Genes & Nutrition·Mohammad Lukman MansuriMordhwaj S Parihar
Jun 6, 2014·Food & Function·J DuarteF Perez-Vizcaino
Aug 12, 2014·Japanese Journal of Clinical Oncology·Shoichiro Tsugane, Norie Sawada
Jun 16, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Jaime GonzalezRodrigo Moore-Carrasco
Jun 17, 2015·European Journal of Epidemiology·Heidi Tsz Mung LaiVictoria Jane Burley
Jun 16, 2017·Annals of the New York Academy of Sciences·Francesca GiampieriMaurizio Battino

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Citations

Sep 3, 2021·The British Journal of Nutrition·Ze-Kai FanDuo Li

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