Consumption of fruits and vegetables and cardiovascular mortality in renal transplant recipients: a prospective cohort study

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Camilo G SotomayorStephan Jl Bakker

Abstract

It currently remains understudied whether low consumption of fruits and vegetables after kidney transplantation may be a modifiable cardiovascular risk factor. We aimed to investigate the associations between consumption of fruits and vegetables and cardiovascular mortality in renal transplant recipients (RTRs). Consumption of fruits and vegetables was assessed in an extensively phenotyping cohort of RTRs. Multivariable-adjusted Cox proportional hazards regression analyses were performed to assess the risk of cardiovascular mortality. We included 400 RTRs (age 52 ± 12 years, 54% males). At a median follow-up of 7.2 years, 23% of RTRs died (53% were due to cardiovascular causes). Overall, fruit consumption was not associated with cardiovascular mortality {hazard ratio [HR] 0.82 [95% confidence interval (CI) 0.60-1.14]; P = 0.24}, whereas vegetable consumption was inversely associated with cardiovascular mortality [HR 0.49 (95% CI 0.34-0.71); P < 0.001]. This association remained independent of adjustment for several potential confounders. The association of fruit consumption with cardiovascular mortality was significantly modified by estimated glomerular filtration rate (eGFR; Pinteraction = 0.01) and proteinuria (Pinteraction =...Continue Reading

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Citations

May 6, 2019·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Philippe Chauveau
Nov 28, 2019·Journal of Clinical Medicine·Tomás A GacitúaStephan J L Bakker
Jun 24, 2020·Journal of Clinical Medicine·Camilo G SotomayorStephan J L Bakker
Sep 18, 2020·Kidney International·Camilo G SotomayorStephan J L Bakker
Jan 29, 2021·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Rainer Oberbauer
Jan 23, 2021·Journal of Clinical Medicine·Stan BenjamensRobert A Pol
Dec 15, 2020·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jennifer S Lees, Patrick B Mark
Mar 9, 2021·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Karin Boslooper-MeulenbeltGerjan J Navis

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