Consumption of nitrate-containing vegetables is inversely associated with hypertension in adults: a prospective investigation from the Tehran Lipid and Glucose Study

Journal of Nephrology
M GolzarandFereidoun Azizi

Abstract

There is growing evidence of the potential properties of nitrate-rich foods against development of hypertension (HTN) and vascular disease. In this study, we investigated the association of nitrate-containing vegetables (NCVs) with risk of HTN after 3 years of follow-up. This prospective study was conducted on 1546 non-hypertensive subjects, aged 20-70 years. Blood pressure was measured at baseline and after 3 years and HTN was defined by the Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure criteria. Dietary intake was collected using a validated semi-quantitative food frequency questionnaire (FFQ). NCVs and high-, medium- and low-NCV subcategories were defined, and the odds of HTN after 3 years according to tertiles of NCV and NCV-category intake were estimated by logistic regression and adjusted for potential variables. Mean age of participants was 38.0 ± 12.0 years at baseline and 57.0 % were women. Mean dietary intake of energy-adjusted NCV was 298.0 ± 177.3 g/day. After adjustment for total energy intake, fiber, sodium, potassium and processed meat, a significant inverse association was observed between NCV and the risk of HTN in the highest tertile category (odds ratio 0.6...Continue Reading

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Citations

Jun 2, 2017·Nutrition Research Reviews·Jacklyn JacksonMark McEvoy
Nov 21, 2019·Biological Chemistry·Matthew B AmdahlMark T Gladwin
Aug 24, 2017·Current Opinion in Clinical Nutrition and Metabolic Care·Conor P Kerley
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Apr 11, 2018·The American Journal of Clinical Nutrition·Lauren C BlekkenhorstCatherine P Bondonno
Aug 15, 2017·Molecular Aspects of Medicine·Catherine P BondonnoJonathan M Hodgson

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