Consumption of Whole-Grain Bread and Risk of Colorectal Cancer among Norwegian Women (the NOWAC Study)

Nutrients
Toril BakkenGuri Skeie

Abstract

There is evidence that consumption of foods containing dietary fiber decreases the risk of colorectal cancer (CRC). Whole grains contain dietary fiber, as well as a range of micronutrients and bioactive compounds, but the association between the consumption of whole grains and the risk of CRC remains less studied. The aim of the present study was to investigate the association between whole-grain bread consumption and CRC incidence among Norwegian women, using data from a prospective cohort study (the Norwegian Women and Cancer Study). Dietary intake was estimated from the food-frequency questionnaires of 78,254 women in the cohort (median age: 55 years), and these women were then followed up for CRC incidence. During the 9 years of median follow-up, 795 women were diagnosed with CRC (316 proximal, 193 distal, 218 rectal). Associations between whole-grain bread consumption and the risk of CRC (including colorectal subsites) were investigated using Cox proportional hazards regression models. When compared to the low consumption group, the hazard ratio for CRC was 0.89 (95% confidence interval (CI): 0.72-1.09) for the high consumption group and 0.86 (95% CI: 0.72-1.02) for the medium consumption group in a multivariable model. Ov...Continue Reading

References

Aug 13, 1998·The American Journal of Clinical Nutrition·L JohanssonC A Drevon
Oct 26, 1999·Cancer Causes & Control : CCC·P PietinenJ Virtamo
Jan 10, 2001·Current Opinion in Oncology·A Lindblom
Oct 24, 2002·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·E SvenssonS Tretli
Jan 31, 2004·Cancer Causes & Control : CCC·Marjorie L McCulloughMichael J Thun
Nov 27, 2004·Journal of Surgical Oncology·Pascal GervazPhilippe Morel
Dec 4, 2004·Cancer Causes & Control : CCC·Kana WuEdward Giovannucci
May 17, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mary McCarlAaron R Folsom
May 11, 2007·The American Journal of Clinical Nutrition·Arthur SchatzkinFrances E Thompson
Jul 24, 2007·International Journal of Epidemiology·Eiliv LundMerethe Kumle
Aug 19, 2007·Journal of Clinical Gastroenterology·Elizabeth T JacobsMaría Elena Martínez
Dec 19, 2008·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Inger Kristin LarsenBjørn Møller
May 13, 2009·Nature Reviews. Genetics·Albert Tenesa, Malcolm G Dunlop
Aug 19, 2009·International Journal of Cancer. Journal International Du Cancer·Inger Kristin Larsen, Freddie Bray
Mar 20, 2010·Critical Reviews in Food Science and Nutrition·Neal Okarter, Rui Hai Liu
Nov 26, 2010·The American Journal of Clinical Nutrition·Teresa T FungEdward Giovannucci
Aug 26, 2011·International Journal of Cancer. Journal International Du Cancer·Louise HansenAnja Olsen
Oct 7, 2011·Scandinavian Journal of Public Health·Cecilie KyrøAnja Olsen
Jan 21, 2012·The International Journal of Behavioral Nutrition and Physical Activity·Kristin B BorchEiliv Lund
Nov 16, 2012·Nature Reviews. Cancer·Asad UmarPeter Greenwald
Feb 16, 2013·Food & Nutrition Research·Wenche FrølichInge Tetens
Mar 20, 2013·Familial Cancer·Miguel A Rodriguez-Bigas, Gabriela Möeslein
Oct 17, 2013·Food & Nutrition Research·Agneta AkessonElisabet Wirfält
Apr 29, 2014·Meat Science·Marije OostindjerBjørg Egelandsdal
Feb 26, 2015·Public Health Nutrition·Toril BakkenGuri Skeie

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Citations

Feb 6, 2017·Molecular Nutrition & Food Research·Yingdong Zhu, Shengmin Sang
Jul 4, 2020·The American Journal of Clinical Nutrition·Autumn G HullingsErikka Loftfield
Jan 7, 2021·Nutrients·Filippo VerniaGiovanni Latella

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