PMID: 8949436Sep 1, 1996Paper

Contact allergy to popular perfumes; assessed by patch test, use test and chemical analysis

The British Journal of Dermatology
J D JohansenT Menne

Abstract

The frequency of contact allergy to the 10 best-selling women's perfumes was studied in 335 consecutive female eczema patients by patch testing. The diagnostic ability of the fragrance mix, in relation to these products, was evaluated. Of eczema patients, 6.9% had a positive patch test to one or more of the perfumes, and 56.5% of these had a concurrent positive reaction to the fragrance mix. Hence, testing with the patients' own cosmetics is a significant part of diagnosing perfume allergy. The clinical relevance of the patch-test reactions to the commercial perfumes was equal to that of the fragrance mix, as judged from the patient's history and use testing with one of the perfumes. At least three of the chemically defined sensitizers in the fragrance mix were detected in all the perfumes by gas chromatography-mass spectrometry, which indicates that the fragrance mix is a good imitation of actual exposure.

References

Sep 1, 1992·Journal of the American Academy of Dermatology·W G LarsenJ S Strauss
Feb 1, 1985·Contact Dermatitis·A C de GrootW G van Ketel
Oct 1, 1970·The British Journal of Dermatology·G Agrup

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Citations

Sep 6, 2001·Clinics in Dermatology·R WolfY Tüzün
Jun 11, 1998·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·J D JohansenT Menné
Dec 22, 1999·The British Journal of Dermatology·P J FroschI R White
Mar 24, 2000·The British Journal of Dermatology·D A BuckleyJ P McFadden
Jul 25, 2000·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·E Bárány, M Lodén
May 19, 2005·Contact Dermatitis·Magnus BruzeTorkil Menné
Oct 24, 2003·American Journal of Clinical Dermatology·Jeanne D Johansen
Oct 31, 2001·Contact Dermatitis·S C RastogiD A Basketter
Apr 12, 2001·Contact Dermatitis·J D JohansenT Menné
May 30, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M McEwan, W H Macfarlane Smith
May 9, 2006·Dermatologic Clinics·Katherine A Biebl, Erin M Warshaw
May 21, 2003·Contact Dermatitis·Suresh C RastogiJeanne Duus Johansen
Mar 9, 2007·Contact Dermatitis·Suresh Chandra RastogiRossana Bossi
Apr 26, 2006·The British Journal of Dermatology·D A BuckleyJ P McFadden
Sep 20, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J ElberlingJ D Johansen
Jun 4, 2014·International Endodontic Journal·T Zarra, T Lambrianidis

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