Contact laser-assisted neuroendoscopy can be performed safely by using pretreated 'black' fibre tips: experimental data

Lasers in Surgery and Medicine
P W WillemsG H Jansen

Abstract

Laser-assisted endoscopic neurosurgery by using conventional fibres requires the use of high-power laser light. Because this is potentially hazardous, we developed a pretreated fibre tip and evaluated tissue effects in vitro and in vivo. By applying a highly absorbing coating to the front of the ball tip, almost all laser light is transformed into thermal energy, instantly producing ablative temperatures at the tip itself. The temperature distribution was examined by using an in vitro thermal imaging technique. The in vivo effect on rabbit cerebral tissue was examined macroscopically and histologically. By using a conventional fibre tip, ablation was not observed, despite the use of high energy and power (20 W for 10 seconds), whereas histology and thermal imaging demonstrated deleterious effects deeply into the cerebral tissue. By using the coated fibre tip, ablation was observed at low energy and power (1 W for 1 second) with thermal effects restricted to superficial structures. We show that laser-assisted neuroendoscopy can only be considered to be safe when pretreated "black" fibre tips are used, as laser light damages deep structures.

References

Jan 1, 1992·Lasers in Surgery and Medicine·D E JohnsonR E Price
Jan 1, 1991·Lasers in Surgery and Medicine·T G van LeeuwenC Borst
Jan 1, 1987·Lasers in Surgery and Medicine·H Ward
Feb 1, 1966·Archives of Neurology·H L Rosomoff, F Carroll
Jan 1, 1994·Lasers in Surgery and Medicine·S Krishnamurthy, S K Powers
May 1, 1997·Physics in Medicine and Biology·R M Verdaasdonk, C F van Swol
Nov 14, 1997·Minimally Invasive Neurosurgery : MIN·T NagataniJ Yoshida
Dec 24, 1997·Neurosurgery·M R McLaughlinA L Albright
Jun 1, 1991·Applied Optics·R M Verdaasdonk, C Borst

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Citations

Aug 12, 2009·Journal of Neurosurgery·Robert W RyanMark C Preul
Nov 26, 2008·Gastrointestinal Endoscopy·UNKNOWN American Society for Gastrointestinal Endoscopy Technology Committee
Apr 3, 2008·Neurosurgery·Janneke van BeijnumW Peter Vandertop
Nov 16, 2018·Lasers in Surgery and Medicine·Andrey V Belikov, Alexei V Skrypnik
May 2, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Digna M A KamalskiWilko Grolman
May 17, 2019·Journal of Biophotonics·Federico BoschiAntonello E Spinelli

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