Contact lens-induced regression of Lisch epithelial corneal dystrophy

Cornea
Walter LischSusanne Pitz

Abstract

To describe the use of soft contact lenses (CL) to reduce the epithelial opacities of Lisch epithelial corneal dystrophy (LECD). First presentation of confocal microscopy in LECD. Two unrelated female patients with LECD demonstrated a central gray opacity with distinct visual impairment. The first patient wore a daily hydroxyethlmethacrylate (HEMA) CL for 3 months and the second, a daily silicone hydrogel CL for 1 month. Pre-CL and post-CL appearances of the cornea were photodocumented at the slit lamp. Additionally, in the second patient, a confocal microscopic evaluation of LECD was performed. In both patients, the wearing of CL resulted in a distinct reduction of central corneal opacification with a visual improvement. Discontinued wearing of CL induced again a progression of opacity. The confocal microscopy disclosed the typical intracytoplasmatic vacuolization of the involved epithelial cells. Wearing CL for a longer duration causes a significant regression of corneal opacities in LECD. The etiology of this phenomenon is interpreted as a CL-induced thinning of corneal epithelium and reduction of epithelial layers.

References

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Citations

Apr 25, 2012·Journal of Materials Science. Materials in Medicine·M BarounianA Kazemzadeh
Jan 10, 2012·Cornea·Kristina KurbanyanSophie X Deng
Nov 21, 2012·Seminars in Ophthalmology·Anita N ShuklaPedram Hamrah
Mar 2, 2016·Archivos de la Sociedad Española de Oftalmología·J Celis SánchezF González Del Valle
Aug 27, 2015·Eye & Contact Lens·Justin T KwanBarry A Weissman
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Deborah S JacobsFiona Stapleton
Apr 26, 2021·The Ocular Surface·Harminder S DuaDalia G Said
Feb 19, 2019·Klinische Monatsblätter für Augenheilkunde·David FinisGerd Geerling
Nov 28, 2017·Journal français d'ophtalmologie·C IscarS Milazzo

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