PMID: 6987648Jan 1, 1980Paper

Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7

Proceedings of the National Academy of Sciences of the United States of America
U Siebenlist, W Gilbert

Abstract

Specific contacts between the Escherichia coli RNA polymerase (nucleosidetriphosphate:RNA nucleotidyl-transferase, EC2.7.7.6) and the phosphates and purine bases of the A3 promoter of phage T7 cluster into three regions located approximately 10, 16, and 35 base pairs before RNA initiation site. Two of these contain nucleotide sequences that are fairly conserved among many promoters, known as the "Pribnow box" and "-35 region" homologies; the third, just upstream from the Pribnow box, is not conserved. The polymerase binds preferentially to the coding strand and for the most part touches only one face of the DNA helix.

References

Feb 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·A M Maxam, W Gilbert
Jan 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·J C Wang
Nov 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·L Johnsrud
Feb 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·D KleidM Ptashne
Jun 25, 1973·Journal of Molecular Biology·E G Minkley, D Pribnow

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Citations

Feb 1, 1990·Journal of Molecular Recognition : JMR·P E Nielsen
Sep 17, 1982·Molecular and Cellular Biochemistry·C W Wu, N Tweedy
Jan 1, 1980·Molecular & General Genetics : MGG·G LeeJ Pero
Jan 1, 1995·Molecular Biology Reports·M E Harris, N R Pace
Jul 1, 1993·Somatic Cell and Molecular Genetics·P F OvermanD J Roufa
Jan 1, 1990·Immunologic Research·B M PeterlinS Tsang
Aug 24, 2010·Analytical and Bioanalytical Chemistry·Reham Helwa, Jörg D Hoheisel
Dec 21, 2011·Molecular Genetics and Genomics : MGG·Svetlana NeubauerOliwia Makarewicz
Jun 5, 1991·Journal of Molecular Biology·J A DiDonatoM T Muller
Jan 1, 1981·Progress in Biophysics and Molecular Biology·S A Kumar
May 1, 1994·Molecular and Biochemical Parasitology·S D Brown, L H Van der Ploeg
Mar 24, 1992·Biochimica Et Biophysica Acta·T TairaH Ariga
Oct 18, 1994·Biochimica Et Biophysica Acta·A Yonezawa, Y Sugiura
Jun 3, 1996·Biochimica Et Biophysica Acta·D PribnowB E Magun
Mar 1, 1992·The Journal of Steroid Biochemistry and Molecular Biology·K Dahlman-WrightJ A Gustafsson
Mar 17, 2004·Journal of Molecular Biology·Gillian ShuttleworthBernard A Connolly
Apr 28, 1995·Journal of Molecular Biology·E KaufmannW Knöchel
Apr 25, 2000·The Journal of Steroid Biochemistry and Molecular Biology·N J KoszewskiJ Russell
Dec 1, 1996·The Journal of Steroid Biochemistry and Molecular Biology·N J KoszewskiR L Horst
Nov 25, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Robert A MoxleySuchareeta Mitra
Oct 20, 2007·Nature Protocols·Pilar TijerinaRick Russell
May 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·C Scheidereit, M Beato
May 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·W Hendrickson, R Schleif
Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·T D Tullius, B A Dombroski
Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·J T Kadonaga, R Tjian
Dec 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·F D Bushman, M Ptashne
Mar 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·M J SolomonA Varshavsky
Oct 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·A Brunelle, R F Schleif
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·M M BeckerL Jen-Jacobson
Feb 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·M RaymondjeanM Yaniv
Jun 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R Moura-NetoR P Perry
Oct 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R James, J Kazenwadel

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