Containing cefoxitin costs through a program to curtail use in surgical prophylaxis.

The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses
G TaylorW Vaudry

Abstract

To reduce drug costs attributable to anti-anaerobic cephalosporins - specifically to reduce cefoxitin use in surgical prophylaxis. Before and after intervention cefoxitin use comparison. Tertiary care hospital. Hospitalized patients. Chart review of patients identified through pharmacy records as cefoxitin recipients was carried out to determine which physicians were the principal users of cefoxitin and the purpose for such use. These data were used to direct cost containment strategies. Hospital quarterly pharmacy acquisition costs and grams of cefoxitin used. The departments of surgery (49%) and obstetrics/gynecology (37%) were the principal users of cefoxitin, and surgical prophylaxis was found to be the principal indication for use (63%). These departments were invited by the Antibiotic Utilization Subcommittee of the hospital's Pharmacy and Therapeutics Committee to draft surgical prophylaxis guidelines in keeping with published recommendations. Such guidelines were written and distributed to medical staff and substituted cefazolin for most forms of prophylaxis, gentamicin/metronidazole for colorectal prophylaxis and cefoxitin only for appendectomies. Over the following 21 months, hospital-wide cefoxitin use fell from 6093...Continue Reading

Citations

Nov 4, 2015·Antimicrobial Agents and Chemotherapy·S T LefurgyR A Bonomo
Jul 25, 2017·Journal of Managed Care & Specialty Pharmacy·Ryan RodriguezMary Moody

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