Contemporary long-term outcomes of an aggressive approach to mitral valve repair in children: is it effective and durable for both congenital and acquired mitral valve lesions?

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Mohd Azhari YakubPau Kiew Kong

Abstract

We analysed the long-term outcomes of mitral valve (MV) repair in children and compared the repairs for both congenital and acquired lesions. A review of 634 children (≤18 years) who underwent MV repair from 1992 to 2011 was conducted [excluding patients with complete atrioventricular septal defect (AVSD), single ventricle and atrioventricular (AV) discordance]. Associated cardiac anomalies were present in 473 patients (75%). Congenital mitral lesions were found in 270 (43%) patients compared with an acquired aetiology in 364 (57%) [mainly rheumatic: 329 patients (90%)]. Mitral regurgitation (MR) was predominant in 606 (96%) patients, and 544 (86%) of these showed ≥3+ MR. Modified techniques of MV reconstructions were used. The early mortality rate was 2% (14 patients). The mean follow-up was 55 months (1-240 months; 85% complete). The late mortality rate was 4% (23 patients) and survival rates at 10 and 15 years were 91 and 86%, respectively. There was no significant difference in 10-year survival between repairing the congenital (98%) and acquired lesions (87%) (P = 0.17). The rate of freedom from reoperation after MV repair for the entire population was 79% at 10 years, with no significant difference between congenital (80%)...Continue Reading

References

Feb 6, 1998·The Journal of Thoracic and Cardiovascular Surgery·S ChauvaudA Carpentier
Mar 15, 2000·Journal of the American College of Cardiology·M TamuraC Brizard
Aug 4, 2001·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·Kim Phuong PhanAlain Carpentier
Jul 3, 2002·Current Treatment Options in Cardiovascular Medicine·Anita Saxena
Jan 29, 2005·The Journal of Thoracic and Cardiovascular Surgery·Kazu MinamiHitoshi Hirose
Apr 12, 2005·The Journal of Thoracic and Cardiovascular Surgery·Sachin TalwarArkalgud Sampath Kumar
Dec 19, 2006·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jeffrey Shuhaiber, Robert J Anderson
May 5, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Rody BoonRobert Dion
Jun 12, 2008·The Journal of Thoracic and Cardiovascular Surgery·Guido OppidoChristian P Brizard
Sep 18, 2009·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Cheul LeeWoo-Sup Shim
Jun 18, 2010·The Journal of Thoracic and Cardiovascular Surgery·Giovanni StellinAlessandro Mazzucco
Oct 26, 2010·The Annals of Thoracic Surgery·Roland HenaineJean Ninet
Mar 1, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Mohd Azhari YakubMohd Nazeri Nordin
Jun 27, 2013·World Journal for Pediatric & Congenital Heart Surgery·Bo RemenyiNigel Wilson
Jan 10, 2014·World Journal for Pediatric & Congenital Heart Surgery·Arkalgud Sampath Kumar
Jan 1, 2013·Heart Asia·Giuseppe Marascio, Pietro Amedeo Modesti

❮ Previous
Next ❯

Citations

Mar 31, 2016·Lancet·Boglarka RemenyiDavid R Holmes
Aug 5, 2016·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Kevin O Maher, James S Tweddell
Aug 28, 2020·World Journal for Pediatric & Congenital Heart Surgery·Sivakumar SivalingamMohd Azhari Yakub
May 24, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jolanda KluinMark G Hazekamp
Apr 12, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Elisabeth MartinMeena Nathan
Mar 17, 2021·Circulation. Cardiovascular Interventions·Nicola MaschiettoDiego Porras
Sep 4, 2020·The Annals of Thoracic Surgery·Christopher IbarraMichiaki Imamura

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.