Contemporary Role of Computational Analysis in Endovascular Treatment for Thoracic Aortic Disease

Aorta : Official Journal of the Aortic Institute at Yale-New Haven Hospital
Guido H W van BogerijenSanti Trimarchi

Abstract

In the past decade, thoracic endovascular aortic repair (TEVAR) has become the primary treatment option in descending aneurysm and dissection. The clinical outcome of this minimally invasive technique is strictly related to an appropriate patient/stent graft selection, hemodynamic interactions, and operator skills. In this context, a quantitative assessment of the biomechanical stress induced in the aortic wall due to the stent graft may support the planning of the procedure. Different techniques of medical imaging, like computed tomography or magnetic resonance imaging, can be used to evaluate dynamics in the thoracic aorta. Such information can also be combined with dedicated patient-specific computer-based simulations, to provide a further insight into the biomechanical aspects. In clinical practice, computational analysis might show the development of aortic disease, such as the aortic wall segments which experience higher stress in places where rupture and dissection may occur. In aortic dissections, the intimal tear is usually located at the level of the sino-tubular junction and/or at the origin of the left subclavian artery. Besides, computational models may potentially be used preoperatively to predict stent graft beha...Continue Reading

Associated Clinical Trials

Citations

Oct 9, 2020·Journal of Cardiac Surgery·Santi TrimarchiGabriele Piffaretti
Sep 8, 2021·International Journal for Numerical Methods in Biomedical Engineering·Stéphane AvrilSandra Rugonyi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aortic Aneurysm

An aortic aneurysm is the weakening and bulging of the blood vessel wall in the aorta. This causes dilatation of the aorta, which is usually asymptomatic but carries the risk of rupture and hemorrhage. Find the latest research on aortic aneurysms here.

Biomechanics

Biomechanics examines the generation of internal forces within the body and investigates the effects and control of forces that act on or are produced on tissues. Here are the latest discoveries.

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

Related Papers

EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Holger Eggebrecht, Martin Czerny
The Korean Journal of Thoracic and Cardiovascular Surgery
Joung Taek KimKwang Ho Kim
© 2022 Meta ULC. All rights reserved