Content development for the Functional Assessment of Cancer Therapy-Multiple Myeloma (FACT-MM): use of qualitative and quantitative methods for scale construction.

Journal of Pain and Symptom Management
Lynne I WagnerDavid Cella

Abstract

Multiple myeloma (MM) is a common hematologic malignancy and is associated with symptom burden and impairments in health-related quality of life (HRQL). To develop a disease-specific, patient-reported outcome (PRO) measure for the assessment of HRQL among patients with MM as part of the Functional Assessment of Cancer Therapy (FACT) measurement system. HRQL concerns and symptoms associated with MM were tabulated based on a literature review, and 52 candidate PRO items were identified. Expert clinicians (n=13) rated 52 items on relevance to HRQL for MM patients (0-3 scale). Experts added 11 items for comprehensive PRO assessment in MM. A list of 63 candidate items was rated (0-3 scale) by 13 MM patients enrolled through the International Myeloma Foundation website. Qualitative data and quantitative item ratings were reviewed to select FACT-MM scale items. Expert clinicians provided the highest HRQL relevance ratings for bone pain, bodily pain, difficulty walking (2.9), tiring easily (2.6), feeling discouraged (2.5), interference with activities and difficulty with self-care as a result of bone pain (2.5), and fatigue (2.5). Mean age of patients was 57 years; Eastern Cooperative Oncology Group performance status was 0 (38%), 1 (3...Continue Reading

References

Jan 5, 2000·BMJ : British Medical Journal·N Mays, C Pope
Feb 15, 2001·Public Opinion Quarterly·M Couper
Apr 25, 2003·Evidence-based Nursing·Cynthia K Russell, David M Gregory
Apr 6, 2006·Palliative & Supportive Care·Chih-Hung ChangRichard Harvey
Apr 4, 2007·International Journal of Cancer. Journal International Du Cancer·Dominik D AlexanderDimitrios Trichopoulos
Nov 2, 2007·Leukemia·K C AndersonUNKNOWN ASH/FDA Panel on Clinical Endpoints in Multiple Myeloma
Mar 12, 2008·Blood·Robert A Kyle, S Vincent Rajkumar
Apr 23, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jesús San-MiguelKenneth C Anderson

❮ Previous
Next ❯

Citations

Feb 7, 2013·Journal of Hematology & Oncology·Desiree JonesTito R Mendoza
Feb 19, 2016·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Bianca WieringDiana Delnoij
Mar 30, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Natasha CamusoGunita Mitera
Jun 23, 2016·Hematological Oncology·Eli MuchtarHila Magen
May 16, 2019·Expert Review of Hematology·Samantha SeitzlerRachid Baz
Jun 30, 2019·Expert Review of Hematology·Massimo MartinoMassimo Gentile
Jun 6, 2019·Parasite : Journal De La Société Française De Parasitologie·Supaporn NuamtanongPoom Adisakwattana
Nov 11, 2018·Blood Cancer Journal·Paul G RichardsonKenneth C Anderson
Jul 19, 2019·Expert Review of Hematology·Pasquale NiscolaFabio Efficace
Feb 23, 2019·Cancer Control : Journal of the Moffitt Cancer Center·Luz-Ma-Adriana Balderas-PeñaBenjamín Rubio-Jurado
Jul 29, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Christina RamsenthalerIrene J Higginson
Dec 29, 2020·Clinical Lymphoma, Myeloma & Leukemia·Joshua RichterStuart L Goldberg
May 6, 2021·The Patient·Hannah CollacottSebastian Heidenreich
Jan 15, 2020·Clinical Therapeutics·Oriana Ciani, Carlo Baldassarre Federici

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.