Context matters: the psychoneurobiological determinants of placebo, nocebo and context-related effects in physiotherapy

Archives of Physiotherapy
Giacomo RossettiniMarco Testa

Abstract

Placebo and nocebo effects embody psychoneurobiological phenomena where behavioural, neurophysiological, perceptive and cognitive changes occur during the therapeutic encounter in the healthcare context. Placebo effects are produced by a positive healthcare context; while nocebo effects are consequences of negative healthcare context. Historically, placebo, nocebo and context-related effects were considered as confounding elements for clinicians and researchers. In the last two decades this attitude started to change, and the understanding of the value of these effects has increased. Despite the growing interest, the knowledge and the awareness of using the healthcare context to trigger placebo and nocebo effects is currently limited and heterogeneous among physiotherapists, reducing their translational value in the physiotherapy field. To introduce the placebo, nocebo and context-related effects by: (1) presenting their psychological models; (2) describing their neurophysiological mechanisms; (3) underlining their impact for the physiotherapy profession; and (4) tracing lines for future researches. Several psychological mechanisms are involved in placebo, nocebo and context-related effects; including expectation, learning proc...Continue Reading

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Citations

Aug 11, 2021·Archives of Physiotherapy·Carla VantiPaolo Pillastrini
Sep 5, 2021·Human Resources for Health·Monu Tamang, Thinley Dorji
Sep 4, 2021·Advances in Therapy·Giovanni Iolascon, Antimo Moretti

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Methods Mentioned

BETA
imaging techniques

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