Contextual analysis of determinants of late diagnosis of hepatitis C virus infection in medicare patients

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Viktor V ChirikovCharles D Howell

Abstract

Patient- and county-level characteristics associated with advanced liver disease (ALD) at hepatitis C virus (HCV) diagnosis were examined in three Medicare cohorts: (1) elderly born before 1945; (2) disabled born 1945-1965; and (3) disabled born after 1965. We used Medicare claims (2006-2009) linked to the Area Health Resource Files. ALD was measured over the period of 6 months before to 3 months after diagnosis. Using weighted multivariate modified Poisson regression to address generalizability of findings to all Medicare patients, we modeled the association between contextual characteristics and presence of ALD at HCV diagnosis. We identified 1,746, 3,351, and 592 patients with ALD prevalence of 28.0%, 23.0%, and 15.0% for birth cohorts 1, 2, and 3. Prevalence of drug abuse increased among younger birth cohorts (4.2%, 22.6%, and 35.6%, respectively). Human immunodeficiency virus coinfection (prevalence ratio [PR] = 0.63; 95% confidence interval [CI]: 0.50-0.80; P = 0.001), dual Medicare/Medicaid eligibility (PR = 0.89; 95% CI: 0.80-0.98; P = 0.017), residence in counties with higher median household income (PR = 0.82; 95% CI: 0.71-0.95; P = 0.008), higher density of primary care providers (PR = 0.84; 95% CI: 0.73-0.98; P = 0....Continue Reading

References

Feb 19, 2002·Journal of Substance Abuse Treatment·Deborah W GarnickConstance M Horgan
Mar 23, 2004·American Journal of Epidemiology·Guangyong Zou
Jun 29, 2005·American Journal of Public Health·L Gary HartDenise M Lishner
Sep 18, 2007·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Tyrone F Borders, Brenda M Booth
Nov 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Fasiha KanwalSteven M Asch
Dec 18, 2008·Source Code for Biology and Medicine·Zoran BursacDavid W Hosmer
Oct 14, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Michael L VolkAnna S F Lok
Feb 15, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Maria StepanovaZobair M Younossi
May 18, 2011·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Judith A SteinLillian Gelberg
Jun 15, 2011·Journal of Social Work in Disability & Rehabilitation·Elspeth Slayter
Jun 22, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R Monina KlevensScott D Holmberg
Sep 11, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hamish A InnesUNKNOWN Hepatitis C Clinical Database Monitoring Committee
Oct 4, 2012·The Journal of Pain : Official Journal of the American Pain Society·Douglas C McDonaldDavid Izrael
Mar 20, 2013·Disability and Health Journal·Raymond E Glazier, Ryan N Kling
Jan 22, 2014·The American Journal of Gastroenterology·Henry W RobertsRuth Jiles
Mar 15, 2014·American Journal of Public Health·Ronald ValdiserriWilson Compton
Mar 26, 2014·Drugs & Aging·Stephen MalnickSari Tal
May 24, 2014·The American Journal of Drug and Alcohol Abuse·Karen H WangWilliam C Becker
Jul 30, 2014·The American Journal of Gastroenterology·Hashem B El-SeragFasiha Kanwal
Aug 13, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anil G SuryaprasadScott D Holmberg
Aug 19, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anne C MoormanUNKNOWN CHeCS Investigators
Sep 5, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J Morgan FreimanBenjamin P Linas
Feb 15, 2015·Journal of General Internal Medicine·Stacey B TrooskinAmy S Nunn
Mar 4, 2015·Open Forum Infectious Diseases·Sabrina A AssoumouBenjamin P Linas

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Citations

Nov 3, 2015·Expert Review of Gastroenterology & Hepatology·Viktor V ChirikovCharles D Howell
Oct 16, 2015·Digestive Diseases and Sciences·Channa R JayasekeraAijaz Ahmed
Aug 13, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Viktor ChirikovCharles Howell
Aug 28, 2020·Seminars in Liver Disease·Fabienne MarcellinPatrizia Carrieri

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