Contiguous conventional and plexiform schwannomas. Report of two cases

Journal of Neurosurgery
J Bradley WhiteRobert J Spinner

Abstract

The authors present clinical, imaging, and histological features of two adult patients found to harbor a conventional schwannoma contiguous with a deep plexiform schwannoma. One patient had neurofibromatosis (NF) Type 2 (NF2), and both intracranial (bilateral oculomotor, trigeminal, acoustic, and hypoglossal schwannomas as well as meningiomas) and intraspinal (schwannomas and meningiomas) lesions. The proximal forearm lesions consisted of a conventional schwannoma and an underlying plexiform component. The second patient, who did not have NF2, presented with a similar enlarging mass in the distal arm; two contiguous lesions were resected. Both patients exhibited distinct, readily identifiable, magnetic resonance imaging features. Plexiform schwannomas are rare lesions that occur sporadically or, on occasion, in association with NF2 or meningiomas with or without multiple schwannomas. The authors believe that a more careful examination of patients with NF2 may show that these people have a higher incidence of plexiform schwannoma than previously thought. Pathological confirmation is crucial in distinguishing plexiform schwannomas from plexiform neurofibromas, because the latter are directly associated with NF1 and have a signifi...Continue Reading

References

Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·T Iwashita, M Enjoji
Oct 1, 1983·The American Journal of Surgical Pathology·J M WoodruffR A Erlandson
Oct 1, 1995·Cancer·J F Val-BernalA Vázquez-Barquero
Apr 1, 1996·Neurology·M MacCollinM P Short
Jul 1, 1996·The Journal of Hand Surgery·M A PosnerP Desai
Feb 6, 1998·The Journal of Thoracic and Cardiovascular Surgery·S SheikhE Montgomery
Oct 26, 1999·Brain Tumor Pathology·B W Scheithauer
Jun 26, 2003·Clinical and Experimental Dermatology·K TerasakiT Kanzaki
Nov 1, 2003·Skeletal Radiology·Keiichi KatsumiNaoto Endo
May 1, 2004·International Journal of Dermatology·Ha Seong LimKee Yang Chung
Jun 14, 2005·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·S C TalwalkarJ H Stilwell

❮ Previous
Next ❯

Citations

Nov 18, 2008·Neurosurgery Clinics of North America·Robert J Spinner, Kimberly K Amrami
Sep 14, 2010·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Jeffrey M JacobsonJohn S Steinberg

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annales de chirurgie plastique et esthétique
A DaoudiF Boutayeb
The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand
S C TalwalkarJ H Stilwell
© 2021 Meta ULC. All rights reserved