PMID: 9437557Jan 23, 1998Paper

Continuation rates with a levonorgestrel-releasing contraceptive implant (Norplant). A prospective study in Belgium

Contraception
M VekemansM Paesmans

Abstract

Contraceptive protection offered by a method depends on its duration of use, which reflects costs, side effects, and relatives' opinions. This study investigated in Norplant implants users the continuation rates, some of their determinants, and the motives for removals. Since 1988, 612 Norplant implants sets, designed to protect for 5 years, have been inserted. Observing 13,907 months of use, we determined over time the continuation rates and how age, parity, circumstances at insertion (postpartum, postabortum, others), and patronymic origins (surrogate for sociocultural factors) influenced them. Statistics included Kaplan-Meier's method and log rank tests, and uni- and multivariate Cox models. Continuation increased with age and depended on sociocultural factors. Parity exerted influence only in younger women. Median duration of use was 3 years 11 months. Removals before 5 years related almost equally to irregular bleeding, other side effects, and pregnancy wish. The cumulative 5-year failure rate was 1.5%. Unsatisfied users returned earlier, distorting the first results. A literature search showed that implants yield, in the mean, slightly better continuation figures than do intrauterine devices, and clearly higher than those...Continue Reading

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Citations

May 8, 2000·Indian Journal of Pediatrics·D E GreydanusM J Gains
Feb 28, 2002·Contraception·Nuriye Ortayli
Nov 5, 1999·Contraception·N RehanI Chaudhary
Jul 2, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J ManonaiS Intaraprasert
Mar 4, 2000·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M K DuC H Chen
Jun 1, 2002·Obstetrics and Gynecology·Tiina BackmanMarkku Koskenvuo
Dec 14, 2004·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Tiina Backman
Apr 3, 2013·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Paula J Adams Hillard
Nov 25, 2000·Obstetrics and Gynecology Clinics of North America·K R Meckstroth, P D Darney
Aug 2, 2016·Journal of Primary Health Care·Christine RokeAnna Whitehead
Mar 12, 2016·Scientific Reports·Olga OrdeigSamuel K Sia
Aug 16, 2000·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·N OrtayliA Bulut

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