PMID: 7066122Apr 1, 1982Paper

Continuous coronary sinus and arterial pH monitoring during pacing-induced ischaemia in coronary artery disease

British Heart Journal
S M Cobbe, P A Poole-Wilson

Abstract

Catheter tip pH electrodes were used for continuous recording of coronary sinus and arterial pH during atrial pacing in 20 patients undergoing coronary arteriography for chest pain. An ischaemic response to atrial pacing was identified by the onset of angina and/or electrocardiographic abnormalities. Technically satisfactory coronary sinus recordings were obtained in 18 patients. Mean coronary sinus pH at the peak pacing rate fell by 0.021 +/- 0.006 units (n = 9) in the ischaemic group, while there was no significant change in the non-ischaemic group. A larger fall in coronary sinus pH (-0.052 +/- 0.009) was found in the ischaemic group in the 30 seconds after the end of atrial pacing, the maximum change occurring after 16.1 +/- 1.5 seconds. A maximum fall of coronary sinus pH greater then 0.02 units identified patients with an ischaemic response. Changes in arterial pH did not account for these results. The sensitivity of coronary sinus pH recording for the detection of ischaemic heart disease is enhanced by sampling during the "washout" phase after the end of pacing.

References

Mar 1, 1979·The American Journal of Cardiology·A P SelwynG Forse
Jan 1, 1975·The American Journal of Cardiology·W A NeillR P Anderson
Mar 1, 1971·The American Journal of Cardiology·J S ForresterR Gorlin
May 1, 1980·Journal of Medical Engineering & Technology·S M Cobbe, P A Poole-Wilson
Aug 1, 1980·Journal of Molecular and Cellular Cardiology·S M Cobbe, P A Poole-Wilson
May 1, 1956·The American Journal of Physiology·D LAURENTL N KATZ

Citations

Jun 1, 1986·British Heart Journal·S C Webb, P A Poole-Wilson
Feb 1, 1990·British Heart Journal·K G OldroydS M Cobbe
Oct 24, 2002·The Journal of Clinical Investigation·S UgawaShoichi Shimada
Dec 19, 2012·Proceedings of the National Academy of Sciences of the United States of America·Eugene A SosunovOleg A Andreev
Jun 29, 2000·Scandinavian Cardiovascular Journal : SCJ·K Ylitalo, K Peuhkurinen
Feb 25, 1998·Pacing and Clinical Electrophysiology : PACE·E GiannitsisU Stierle
Aug 1, 1990·Journal of Cardiothoracic Anesthesia·D F Van RiperS M Goldman
Apr 30, 1986·The American Journal of Medicine·S CampbellA P Selwyn
Sep 1, 2003·Expert Review of Neurotherapeutics·S UgawaShoichi Shimada
Jul 19, 2001·Annals of the New York Academy of Sciences·C J Benson, S P Sutherland
May 1, 1990·Medical & Biological Engineering & Computing·P Rolfe

Related Concepts

Cardiac Pacing, Artificial
Coronary Heart Disease
Sinus Node Artery
Hydrogen-Ion Concentration
Myocardium

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