Continuous cultures of fused cells secreting antibody of predefined specificity.

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Continuous cultures of fused cells secreting antibody of predefined specificity.

Abstract

Associated Clinical Trials

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Citations

Detection of hepatitis C virus core protein circulating within different virus particle populations

HCV core immunodominant region analysis using mouse monoclonal antibodies and human sera: characterization of major epitopes useful for antigen detection

Applicability of monoclonal antibody Fab fragments as a carrier of neocarzinostatin in targeting chemotherapy

False tumor-positive lymph nodes in radioimmunodiagnosis and radioimmunoguided surgery: etiologic mechanisms

Frequent expression of complement resistance factors CD46, CD55, and CD59 on gastrointestinal cancer cells limits the therapeutic potential of monoclonal antibody 17-1A

Monoclonal antibodies as tools for studying the osteoblast lineage

The clinical significance of u-FCC, an antigen of anti-fucosylceramide antibody found in urine, in patients with gastric and colorectal carcinoma

Detection of circulating gastric carcinoma-associated antigen MG7-Ag in human sera using an established single determinant immuno-polymerase chain reaction technique

Isolation and characterization of ovarian cancer antigen CA 125 using a new monoclonal antibody (VK-8): identification as a mucin-type molecule

111Indium-labeled monoclonal antibody K1: biodistribution study in nude mice bearing a human carcinoma xenograft expressing mesothelin

CD3xCD19 bispecific antibodies and CD28 bivalent antibodies enhance T-cell reactivity against autologous leukemic cells in pediatric B-ALL bone marrow

MUC1 isoform specific monoclonal antibody 6E6/2 detects preferential expression of the novel MUC1/Y protein in breast and ovarian cancer

Dichloroacetate increases cell and antibody yields in batch cultures of a hybridoma cell line

Use of the weighted jackknife method to calculate the variance in cellular-specific protein secretion rate: application to monoclonal antibody secretion rate kinetics in response to osmotic stress

Prevention of hybridoma cell death by bcl-2 during suboptimal culture conditions

Effect of growth factors and antigen on hybridoma cell culture dynamics

Immunochromatographic membrane strip assay system for a single-class plasma lipoprotein cholesterol, exemplified by high-density lipoprotein cholesterol measurement

Special stains, the old and the new: the impact of immunocytochemistry in effusion cytology

Stem cells and the cellular organization of the brain

Product of the oncogene-activating gene Tpr is a phosphorylated protein of the nuclear pore complex

Staurosporine induces neurite outgrowth in neuronal hybrids (PC12EN) lacking NGF receptors

CD44v10 expression in the mouse and functional activity in delayed type hypersensitivity

Growth pattern and NGF-dependent survival of dorsal root ganglia neurons of distinct glyco-phenotype

Future therapies for the treatment of bladder neoplasms

Role of radioimmunoguided surgery using iodine-125-labeled B72.3 monoclonal antibody in gastric cancer surgery

Distribution of radiolabelled anti-CA125 monoclonal antibody OC125-F(ab)2-fragment following resection guided by antibodies (REGAJ) in ovarian cancer patients

The hybridoma revolution: an offshoot of basic research

Genetic, structural and functional properties of an IgG DNA-binding monoclonal antibody from a lupus patient with nephritis

Reduction of tumor burden and stabilization of disease by systemic therapy with anti-CD20 antibody (rituximab) in patients with primary cutaneous B-cell lymphoma

Identification and characterization of a Kunitz-type protease inhibitor in ascites fluid from patients with ovarian carcinoma

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Plasma cells for a lifetime?

Human anticardiolipin monoclonal autoantibodies cause placental necrosis and fetal loss in BALB/c mice

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Therapeutic cancer targeting peptides

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Efficient recovery of recombinant proteins using membrane-based immunoaffinity chromatography (MIC)

Intracellular ribonucleotide pools as a tool for monitoring the physiological state of in vitro cultivated mammalian cells during production processes

High-density continuous cultures of hybridoma cells in a depth filter perfusion system

Physiological responses of hybridoma cells in a protein-free medium to soluble and immobilized antigen

Purification of two murine monoclonal antibodies of the IgM class by hydroxylapatite chromatography and gel filtration

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